Recent advances in metabolomics for studying heavy metal stress in plants
Z Feng, S Ji, J Ping, D Cui - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Heavy metals (HMs) are affected by natural and human activities and contaminate the soil
environment, endanger plant growth and pose a serious threat to the ecosystem. HMs …
environment, endanger plant growth and pose a serious threat to the ecosystem. HMs …
Promises of microbiome-based therapies
Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …
Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping
Proton nuclear magnetic resonance (NMR)-based metabolic phenotyping of urine and blood
plasma/serum samples provides important prognostic and diagnostic information and …
plasma/serum samples provides important prognostic and diagnostic information and …
The metabolomic window into hepatobiliary disease
The emergent discipline of metabolomics has attracted considerable research effort in
hepatology. Here we review the metabolomic data for non-alcoholic fatty liver disease …
hepatology. Here we review the metabolomic data for non-alcoholic fatty liver disease …
Cerebrospinal fluid metabolomics highlights dysregulation of energy metabolism in overt hepatic encephalopathy
N Weiss, PB Saint Hilaire, B Colsch, F Isnard… - Journal of …, 2016 - Elsevier
Background & Aims Hepatic encephalopathy (HE) is a neurological complication observed
in patients with liver disease and/or porto-systemic shunt. The proportion of cirrhotic patients …
in patients with liver disease and/or porto-systemic shunt. The proportion of cirrhotic patients …
Clinical metabolomics: the new metabolic window for inborn errors of metabolism investigations in the post-genomic era
Inborn errors of metabolism (IEM) represent a group of about 500 rare genetic diseases with
an overall estimated incidence of 1/2500. The diversity of metabolic pathways involved …
an overall estimated incidence of 1/2500. The diversity of metabolic pathways involved …
A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation
W Claeys, L Van Hoecke, A Geerts… - Scientific Reports, 2022 - nature.com
Hepatic encephalopathy (HE) is a common complication of chronic liver disease,
characterized by an altered mental state and hyperammonemia. Insight into the brain …
characterized by an altered mental state and hyperammonemia. Insight into the brain …
Gut microbiome-brain-cirrhosis axis
Cirrhosis is characterized by inflammation, degeneration, and fibrosis of liver tissue. Along
with being the most common cause of liver failure and liver transplant, cirrhosis is a …
with being the most common cause of liver failure and liver transplant, cirrhosis is a …
Metabolomic and lipidomic biomarkers for premalignant liver disease diagnosis and therapy
In recent years, there has been a plethora of attempts to discover biomarkers that are more
reliable than α-fetoprotein for the early prediction and prognosis of hepatocellular carcinoma …
reliable than α-fetoprotein for the early prediction and prognosis of hepatocellular carcinoma …
[HTML][HTML] The neurogliovascular unit in hepatic encephalopathy
Hepatic encephalopathy (HE) is a neurological complication of hepatic dysfunction and
portosystemic shunting. It is highly prevalent in patients with cirrhosis and is associated with …
portosystemic shunting. It is highly prevalent in patients with cirrhosis and is associated with …