ABSTRACT ATP‐binding cassette (ABC) transporters are ubiquitous across all realms of life.
Dogma suggests that bacterial ABC transporters include both importers and exporters, whilst …

Abstract Polycystin-2 (PC2), a calcium-activated cation TRP channel, is involved in diverse
Ca2+ signaling pathways. Malfunctioning Ca2+ regulation in PC2 causes autosomal …

The recently increasing number of atomic structures for active transporters has not only
revealed strong conservation in the architecture of sequence-unrelated transporter families …

The hair cell mechanotransduction (MET) channel complex is essential for hearing, yet it's
molecular identity and structure remain elusive. The transmembrane channel–like 1 (TMC1) …

Grape thaumatin-like proteins (TLPs) play roles in plant-pathogen interactions and can
cause protein haze in white wine unless removed prior to bottling. Different isoforms of TLPs …

Rhodopsins are seven α-helical membrane proteins that are of great importance in
chemistry, biology, and modern biotechnology. Any in silico study on rhodopsin properties …

We present a web server for pair-wise alignment of membrane protein sequences, using the
program AlignMe. The server makes available two operational modes of AlignMe:(i) …

Whether G protein-coupled receptors (GPCR s) exist in plants is a fundamental biological
question. Interest in deorphanizing new GPCR s arises because of their importance in …

Parkinson's disease (PD) is characterized by the formation of Lewy bodies (LBs), of which
their major component is the non-amyloid-β component (NAC) of α-synuclein (AS). Clinical …

Silicon (Si) has long been known to play a major physiological and structural role in certain
organisms, including diatoms, sponges, and many higher plants, leading to the recent …