Locus coeruleus noradrenaline depletion and its differential impact on CO2-induced panic and hyperventilation in male and female mice

GC Ripamonte, EM Fonseca, AT Frias… - Progress in Neuro …, 2024 - Elsevier
CO 2 exposure has been used to investigate the panicogenic response in patients with
panic disorder. These patients are more sensitive to CO 2, and more likely to experience the …

A locus coeruleus to dorsal hippocampus pathway mediates cue-induced reinstatement of opioid self-administration in male and female rats

T Markovic, J Higginbotham, B Ruyle… - …, 2024 - nature.com
Opioid use disorder is a chronic relapsing disorder encompassing misuse, dependence,
and addiction to opioid drugs. Long term maintenance of associations between the …

Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus

S McKenzie, AL Sommer, TN Donaldson, I Pimentel… - …, 2024 - pmc.ncbi.nlm.nih.gov
Episodic memories are temporally segmented around event boundaries that tend to
coincide with moments of environmental change. During these times, the state of the brain …

[HTML][HTML] Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment

KM Ranard, B Appel - Journal of Lipid Research, 2025 - Elsevier
Docosahexaenoic acid (DHA), a dietary omega-3 fatty acid, is a major building block of brain
cell membranes. Offspring rely on maternal DHA transfer to meet their neurodevelopmental …

Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors

RC Lopez, N Noble, OD Ozcete, X Cai, GE Handy… - bioRxiv, 2024 - biorxiv.org
GPCR-based fluorescent sensors are widely used to correlate neuromodulatory signaling
with brain function. While experiments in transfected cells often reveal selectivity for …