Pyroptosis is a form of programmed cell death activated by various stimuli and is
characterized by inflammasome assembly, membrane pore formation, and the secretion of …

Arterial occlusive disease is the leading cause of death in Western countries. Core
contemporary therapies for this disease include angioplasties, stents, endarterectomies and …

Inflammation is an important process involved in several cardiovascular diseases (CVDs),
and nod‐like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a vital …

Background/Aim: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial
metabolism of dietary phosphatidylcholine has been recently associated with …

Vascular endothelial cells (VECs), which are lined up in the inner surface of blood vessels,
are in direct contact with the metabolite-related endogenous danger signals in the …

The development of new therapeutic approaches to diseases relies on the identification of
key molecular targets involved in amplifying disease processes. One such molecule is …

Growing evidence suggests that ceramides play an important role in the development of
atherosclerotic and valvular heart disease. Ceramides are biologically active sphingolipids …

Cholesterol crystal‐(CC‐) induced endothelial cell inflammation and pyroptosis play an
important role in the development of cardiovascular diseases, especially in atherosclerosis …

Age-related diseases for which there are no effective treatments include cardiovascular
diseases; neurodegenerative diseases such as Alzheimer's disease; eye disorders such as …

Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …