Environment and brain plasticity: towards an endogenous pharmacotherapy

A Sale, N Berardi, L Maffei - Physiological reviews, 2014 - journals.physiology.org
Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …

Environmental enrichment and the sensory brain: the role of enrichment in remediating brain injury

DS Alwis, R Rajan - Frontiers in systems neuroscience, 2014 - frontiersin.org
The brain's life-long capacity for experience-dependent plasticity allows adaptation to new
environments or to changes in the environment, and to changes in internal brain states such …

Environmental enrichment promotes improved spatial abilities and enhanced dendritic growth in the rat

MG Leggio, L Mandolesi, F Federico, F Spirito… - Behavioural brain …, 2005 - Elsevier
An enriched environment consists of a combination of enhanced social relations, physical
exercise and interactions with non-social stimuli that leads to behavioral and neuronal …

What is it like to be a rat? Rat sensory perception and its implications for experimental design and rat welfare

CC Burn - Applied Animal Behaviour Science, 2008 - Elsevier
This review of rat sensory perception spans eight decades of work conducted across diverse
research fields. It covers rat vision, audition, olfaction, gustation, and somatosensation, and …

Early impoverished environment delays the maturation of cerebral cortex

R Narducci, L Baroncelli, G Sansevero, T Begenisic… - Scientific Reports, 2018 - nature.com
The influence of exposure to impoverished environments on brain development is
unexplored since most studies investigated how environmental impoverishment affects adult …

Synapse formation in adult barrel cortex following naturalistic environmental enrichment

MS Landers, GW Knott, HP Lipp, I Poletaeva, E Welker - Neuroscience, 2011 - Elsevier
Environmental enrichment paradigms in adult laboratory animals, consisting of physical,
perceptual, and social stimulation, have been shown to affect synapse and cell morphology …

Prenatal and early postnatal odorant exposure heightens odor-evoked mitral cell responses in the mouse olfactory bulb

A Liu, NN Urban - Eneuro, 2017 - eneuro.org
Early sensory experience shapes the anatomy and function of sensory circuits. In the mouse
olfactory bulb (OB), prenatal and early postnatal odorant exposure through odorized food …

Have studies of the developmental regulation of behavioral phenotypes revealed the mechanisms of gene–environment interactions?

FS Hall, MTG Perona - Physiology & behavior, 2012 - Elsevier
This review addresses the recent convergence of our long-standing knowledge of the
regulation of behavioral phenotypes by developmental experience with recent advances in …

Refining the sensory and motor ratunculus of the rat upper extremity using fMRI and direct nerve stimulation

YR Cho, CP Pawela, R Li, D Kao… - … in Medicine: An …, 2007 - Wiley Online Library
It is well understood that the different regions of the body have cortical representations in
proportion to the degree of innervation. Our current understanding of the rat upper extremity …

Mapping of the brain hemodynamic responses to sensorimotor stimulation in a rodent model: A BOLD fMRI study

S Boussida, AS Traoré, F Durif - PloS one, 2017 - journals.plos.org
Blood Oxygenation Level Dependent functional MRI (BOLD fMRI) during electrical paw
stimulation has been widely used in studies aimed at the understanding of the …