Mechanistic DNA damage simulations in Geant4-DNA Part 2: Electron and proton damage in a bacterial cell

N Lampe, M Karamitros, V Breton, JMC Brown… - Physica Medica, 2018 - Elsevier
We extended a generic Geant4 application for mechanistic DNA damage simulations to an
Escherichia coli cell geometry, finding electron damage yields and proton damage yields …

First transcriptome profiling of D. melanogaster after development in a deep underground low radiation background laboratory

M Zarubin, A Gangapshev, Y Gavriljuk, V Kazalov… - PLoS …, 2021 - journals.plos.org
Natural background radiation is a permanent multicomponent factor. It has an influence on
biological organisms, but effects of its deprivation still remain unclear. The aim of our work …

Understanding low radiation background biology through controlled evolution experiments

N Lampe, V Breton, D Sarramia… - Evolutionary …, 2017 - Wiley Online Library
Biological experiments conducted in underground laboratories over the last decade have
shown that life can respond to relatively small changes in the radiation background in …

Fruit flies provide new insights in low-radiation background biology at the INFN Underground Gran Sasso National Laboratory (LNGS)

P Morciano, F Cipressa, A Porrazzo… - Radiation …, 2018 - meridian.allenpress.com
Deep underground laboratories (DULs) were originally created to host particle, astroparticle
or nuclear physics experiments requiring a low-background environment with vastly reduced …

Reducing the ionizing radiation background does not significantly affect the evolution of Escherichia coli populations over 500 generations

N Lampe, P Marin, M Coulon, P Micheau, L Maigne… - Scientific Reports, 2019 - nature.com
Over millennia, life has been exposed to ionizing radiation from cosmic rays and natural
radioisotopes. Biological experiments in underground laboratories have recently …

Natural background radiation at Lab 2 of Callio Lab, Pyhäsalmi mine in Finland

K Polaczek-Grelik, A Walencik-Łata, K Szkliniarz… - Nuclear Instruments and …, 2020 - Elsevier
In operating mines, as well as in deep locations for planned scientific activities, it is essential
to recognize the natural background radiation from the point of view of both occupational …

Simulating the impact of the natural radiation background on bacterial systems: Implications for very low radiation biological experiments

N Lampe, DG Biron, JMC Brown, S Incerti, P Marin… - PloS one, 2016 - journals.plos.org
At very low radiation dose rates, the effects of energy depositions in cells by ionizing
radiation is best understood stochastically, as ionizing particles deposit energy along tracks …

Dosimetric characterisation of a sub-natural background radiation environment for radiobiology investigations

KJ Kennedy, A LeBlanc, J Pirkkanen… - Radiation Protection …, 2021 - academic.oup.com
Living systems have evolved in the presence of naturally occurring ionising radiation.
REPAIR is a research project investigating the biological effects of sub-natural background …

Biological effects of low background radiation: prospects for future research in the low-background laboratory DULB-4900 of Baksan neutrino observatory INR RAS

MP Zarubin, OA Kuldoshina, EV Kravchenko - Physics of Particles and …, 2021 - Springer
Study of the effects of low background radiation on biological systems is a new field in
radiation biology. Due to the availability of new experimental methods, studies of the …

Review of the effect of reduced levels of background radiation on living organisms

MT Chew, DA Bradley, B Jones, A Nisbet… - Radiation Physics and …, 2022 - Elsevier
It is well understood that all life is subject to continuous low levels of ionizing radiation, most
prominently from the natural background of the biosphere, differing appreciably in particular …