MicroRNAs in kidney injury and disease

N Mahtal, O Lenoir, C Tinel, D Anglicheau… - Nature Reviews …, 2022 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

Emerging roles of exosomal miRNAs in diabetes mellitus

X He, G Kuang, Y Wu, C Ou - Clinical and translational …, 2021 - Wiley Online Library
Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by
almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids …

Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications

YX Xu, SD Pu, X Li, ZW Yu, YT Zhang, XW Tong… - Pharmacological …, 2022 - Elsevier
Exosomes are discoid vesicles with a diameter of 40–160 nm. They are mainly derived from
the multivesicular body formed by the invagination of lysosomal particles in the cell, which …

Exosomes and their noncoding RNA cargo are emerging as new modulators for diabetes mellitus

W Chang, J Wang - Cells, 2019 - mdpi.com
Diabetes belongs to a group of metabolic disorders characterized by long term high blood
glucose levels due to either inadequate production of insulin (Type 1 diabetes, T1DM) or …

Advanced nanotechnologies for extracellular vesicle‐based liquid biopsy

L Min, B Wang, H Bao, X Li, L Zhao, J Meng… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy
because of their wide presence in most body fluids and their ability to load cargoes from …

Roles for exosome in various kidney diseases and disorders

V Thongboonkerd - Frontiers in pharmacology, 2020 - frontiersin.org
Exosome is a nanoscale vesicle with a size range of 30–100 nm. It is secreted from cell to
extracellular space by exocytosis after fusion of multivesicular body (MVB)(formed by …

MicroRNA expression profiles and type 1 diabetes mellitus: systematic review and bioinformatic analysis

TS Assmann, M Recamonde-Mendoza… - Endocrine …, 2017 - ec.bioscientifica.com
Growing evidence indicates that microRNAs (miRNAs) have a key role in processes
involved in type 1 diabetes mellitus (T1DM) pathogenesis, including immune system …

Stem cell-derived and circulating exosomal microRNAs as new potential tools for diabetic nephropathy management

L Peng, Y Chen, S Shi, H Wen - Stem Cell Research & Therapy, 2022 - Springer
Background Despite major advances in the treatment of diabetic nephropathy (DN) in recent
years, it remains the most common cause of end-stage renal disease. An early diagnosis …

The potential roles of exosomes in pancreatic cancer initiation and metastasis

W Sun, Y Ren, Z Lu, X Zhao - Molecular cancer, 2020 - Springer
Pancreatic cancer (PaCa) is an insidious and highly metastatic malignancy, with a 5-year
survival rate of less than 5%. So far, the pathogenesis and progression mechanisms of …

[HTML][HTML] Accelerated wound healing in diabetic mice by miRNA-497 and its anti-inflammatory activity

E Ban, S Jeong, M Park, H Kwon, J Park… - Biomedicine & …, 2020 - Elsevier
Diabetic foot ulcers represent one of the major and rising health issues, as the number of
diabetic patients is increasing. MicroRNAs (miRNAs) are among various bioactive …