Neutrophils in cancer carcinogenesis and metastasis

S Xiong, L Dong, L Cheng - Journal of hematology & oncology, 2021 - Springer
In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps

JM Adrover, SAC McDowell, XY He, DF Quail… - Cancer Cell, 2023 - cell.com
Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

Photothermal nanozyme‐based microneedle patch against refractory bacterial biofilm infection via iron‐actuated janus ion therapy

W Zhu, J Mei, X Zhang, J Zhou, D Xu, Z Su… - Advanced …, 2022 - Wiley Online Library
Owing to high antibiotic resistance and thermotolerance, bacterial biofilm infections (BBIs)
are refractory to elimination. Iron is essential for bacterial growth and metabolism, and …

Cellular mechanisms of NETosis

HR Thiam, SL Wong, DD Wagner… - Annual review of cell …, 2020 - annualreviews.org
Neutrophils are critical to innate immunity, including host defense against bacterial and
fungal infections. They achieve their host defense role by phagocytosing pathogens …

Neutrophil intrinsic and extrinsic regulation of NETosis in health and disease

V Poli, I Zanoni - Trends in microbiology, 2023 - cell.com
Neutrophil extracellular traps (NETs) evolved to protect the host against microbial infections
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …

Neutrophils and NETs in modulating acute and chronic inflammation

FVS Castanheira, P Kubes - … Journal of the American Society of …, 2019 - ashpublications.org
Neutrophils are an absolutely essential part of the innate immune system, playing an
essential role in the control of infectious diseases but more recently are also being viewed …

Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases

M Herre, J Cedervall, N Mackman… - Physiological …, 2023 - journals.physiology.org
Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Neutrophil extracellular traps in homeostasis and disease

H Wang, SJ Kim, Y Lei, S Wang, H Wang… - … and Targeted Therapy, 2024 - nature.com
Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Neutrophils self-limit swarming to contain bacterial growth in vivo

K Kienle, KM Glaser, S Eickhoff, M Mihlan, K Knöpper… - Science, 2021 - science.org
INTRODUCTION The collective behavior of cells and insects often relies on self-organizing
processes. By releasing attractant signals, a few individuals can initiate the accumulation …

Neutrophils in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus: same foe different MO

M Fresneda Alarcon, Z McLaren, HL Wright - Frontiers in immunology, 2021 - frontiersin.org
Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …