Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …

Tubulointerstitial inflammation is a common characteristic of acute and chronic kidney injury.
However, the mechanism by which the initial injury of tubular epithelial cells (TECs) drives …

Excessive or inappropriate activation of the immune system can be deleterious to the
organism, warranting multiple molecular mechanisms to control and properly terminate …

MicroRNAs (miRNAs) are a class of noncoding RNAs that regulate target gene expression
at the posttranscriptional level. Here, we report that secreted miRNAs can serve as signaling …

Background When a new pathogen, such as severe acute respiratory syndrome coronavirus
2, appears all novel information can aid in the process of monitoring and in the diagnosis of …

Chronic inflammation is involved in the onset and development of many diseases, including
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …

MicroRNAs (miRNAs) regulate gene expression and have a critical role in many biologic
and pathologic processes. We hypothesized that miRNA expression profiles in injured brain …

The immune system of an organism is an essential component of the defense mechanism
aimed at combating pathogenic stress. Age-associated immune dysfunction, also dubbed …

Neuroinflammation is a major contributor to secondary neuronal injury that accounts for a
significant proportion of final brain cell loss in neonatal hypoxic-ischemic encephalopathy …