Skin wound healing: of players, patterns, and processes

H Sorg, CGG Sorg - European Surgical Research, 2023 - karger.com
Background: Wound healing of the skin is a very complex biological activity. For a better
understanding, an attempt is made to describe and subdivide the different players (cell types …

Neutrophil extracellular traps in wound healing

Z Zhu, S Zhou, S Li, S Gong, Q Zhang - Trends in Pharmacological …, 2024 - cell.com
Wound healing is a complex and orchestrated process that involves hemostasis,
inflammation, proliferation, and tissue remodeling. Neutrophil extracellular traps (NETs) are …

Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts

QM Phan, S Sinha, J Biernaskie… - Experimental …, 2021 - Wiley Online Library
Wound‐induced hair follicle neogenesis (WIHN) has been an important model to study hair
follicle regeneration during wound repair. However, the cellular and molecular components …

[HTML][HTML] Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity

L Yu, J Yan, Y Zhan, A Li, L Zhu, J Qian, F Zhou… - Journal of …, 2023 - Elsevier
Gaining a better understanding of autoprotection against drug-induced liver injury (DILI) may
provide new strategies for its prevention and therapy. However, little is known about the …

TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells

X Li, T An, Y Yang, Z Xu, S Chen, Z Yi, C Deng… - Cell Death & …, 2024 - nature.com
The mechanisms underlying tissue repair in response to damage have been one of main
subjects of investigation. Here we leverage the wound-induced hair neogenesis (WIHN) …

Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration

Y Yang, C Chu, L Liu, C Wang, C Hu, S Rung… - nature …, 2023 - nature.com
Skin scarring devoid of dermal appendages after severe trauma has unfavorable effects on
aesthetic and physiological functions. Here we present a method for large-area wound …

Granulocyte colony stimulating factor promotes scarless tissue regeneration

J Huang, S Sati, C Murphy, CA Spencer, E Rapp… - Cell reports, 2024 - cell.com
Mammals typically heal with fibrotic scars, and treatments to regenerate human skin and hair
without a scar remain elusive. We discovered that mice lacking CXC motif chemokine …

Synergism between obesity and HFpEF on neutrophils phenotype and its regulation by adipose tissue‐molecules and SGLT2i dapagliflozin

C Almengló, X Fu, MT Flores‐Arias… - Journal of Cellular …, 2022 - Wiley Online Library
The adiposity invokes innate immune activity, coronary microvascular dysfunction and
consequently heart failure preserved ejection fraction (HFpEF). Our aim was to study the …

Fantastic proteins and where to find them–histones, in the nucleus and beyond

J Grinat, NP Shriever… - Journal of Cell …, 2024 - journals.biologists.com
Animal genomes are packaged into chromatin, a highly dynamic macromolecular structure
of DNA and histone proteins organised into nucleosomes. This accommodates packaging of …

Rethinking neutrophil extracellular traps

Y Liu, Y Ma, J Yang, J Man, H Wang, Y Li… - International …, 2023 - Elsevier
Neutrophils are a major subset of leukocytes in human circulating blood. In some
circumstances, neutrophils release neutrophil extracellular traps (NETs). lnitially, NETs were …