DNA computing and DNA data storage are emerging fields that are unlocking new
possibilities in information technology and diagnostics. These approaches use DNA …

Probing endogenous molecules in living entities is significant to help decipher biological
functions and exploit novel theranostics. DNA circuits that can recognize molecular inputs of …

Herein, a long period liner DNA tandem (Lr-DNT) was intelligently designed as DNA track
for quadruped DNA walker (q-walker) to run in an orderly and efficient manner, which could …

The detection of circulating tumor microRNAs (miRNAs) holds great promise for the
noninvasive and early-stage diagnosis of cancer. However, the low abundance of lung …

Sophisticated dynamic molecular systems with diverse functions have been fabricated by
using the fundamental tool of toehold-mediated strand displacement (TMSD) in the field of …

Toehold-mediated strand displacement (TMSD) is extensively utilized in dynamic DNA
nanotechnology and for a wide range of DNA or RNA-based reaction circuits. Investigation …

Building synthetic molecular circuits is an important way to realize ion detection, information
processing, and molecular computing. However, it is still challenging to implement the NOT …

The DNA triplex is a special DNA structure often used as a logic gate substrate due to its
high stability, programmability, and pH responsiveness. However, multiple triplex structures …

DNA computing is regarded as one of the most promising candidates for the next generation
of molecular computers, utilizing DNA to execute Boolean logic operations. In recent …

The quantitative detection of critical biomolecules and in particular low-abundance
biomarkers in biofluids is crucial for early-stage diagnosis and management but remains a …