Pathogenesis and pathophysiology of idiopathic normal pressure hydrocephalus

Z Wang, Y Zhang, F Hu, J Ding… - CNS neuroscience & …, 2020 - Wiley Online Library
Idiopathic normal pressure hydrocephalus (iNPH), the most common type of adult‐onset
hydrocephalus, is a potentially reversible neuropsychiatric entity characterized by dilated …

Infantile hydrocephalus: a review of epidemiology, classification and causes

HM Tully, WB Dobyns - European journal of medical genetics, 2014 - Elsevier
Hydrocephalus is a common but complex condition caused by physical or functional
obstruction of CSF flow that leads to progressive ventricular dilatation. Though …

Effect of gravity and microgravity on intracranial pressure

JS Lawley, LG Petersen, EJ Howden… - The Journal of …, 2017 - Wiley Online Library
Key Points Astronauts have recently been discovered to have impaired vision, with a
presentation that resembles syndromes of elevated intracranial pressure on Earth. Gravity …

Diagnosis and treatment of idiopathic normal pressure hydrocephalus

MA Williams, J Malm - Continuum: Lifelong Learning in Neurology, 2016 - journals.lww.com
Abstract Purpose of Review: This article provides neurologists with a pragmatic approach to
the diagnosis and treatment of idiopathic normal pressure hydrocephalus (iNPH), including …

[HTML][HTML] Harnessing cerebrospinal fluid circulation for drug delivery to brain tissues

GN Kouzehgarani, T Feldsien, HH Engelhard… - Advanced Drug Delivery …, 2021 - Elsevier
Initially thought to be useful only to reach tissues in the immediate vicinity of the CSF
circulatory system, CSF circulation is now increasingly viewed as a viable pathway to deliver …

Influence of comorbidities in idiopathic normal pressure hydrocephalus—research and clinical care. A report of the ISHCSF task force on comorbidities in INPH

J Malm, NR Graff-Radford, M Ishikawa… - Fluids and Barriers of …, 2013 - Springer
Idiopathic normal pressure hydrocephalus (INPH) is a syndrome of ventriculomegaly, gait
impairment, cognitive decline and incontinence that occurs in an elderly population prone to …

The genetic basis of hydrocephalus

M Kousi, N Katsanis - Annual review of neuroscience, 2016 - annualreviews.org
Studies of syndromic hydrocephalus have led to the identification of> 100 causative genes.
Even though this work has illuminated numerous pathways associated with hydrocephalus …

Intracranial pressure elevation alters CSF clearance pathways

V Vinje, A Eklund, KA Mardal, ME Rognes… - Fluids and Barriers of …, 2020 - Springer
Background Infusion testing is a common procedure to determine whether shunting will be
beneficial in patients with normal pressure hydrocephalus. The method has a well …

The pathogenesis based on the glymphatic system, diagnosis, and treatment of idiopathic normal pressure hydrocephalus

C Tan, X Wang, Y Wang, C Wang, Z Tang… - … Interventions in Aging, 2021 - Taylor & Francis
Idiopathic normal pressure hydrocephalus (iNPH) is a rare neurological disorder with no
clear prevalence factors and is a significant danger to the elderly. The intracranial …

Pathogenesis of idiopathic normal pressure hydrocephalus: a review of knowledge

K Bräutigam, A Vakis, C Tsitsipanis - Journal of Clinical Neuroscience, 2019 - Elsevier
Abstract Idiopathic Normal Pressure Hydrocephalus (iNPH) is a frequent neuropsychiatric
entity. Clinically it is characterised by Hakim's triad: Dementia, gait disturbance and urinary …