Escherichia coli is the most common Gram-negative bacterial pathogen, presenting both a
clinical and an epidemiological challenge. In the last decade, several successful multidrug …

Escherichia coli strains belonging to diverse pathotypes have increasingly been recognized
as a major public health concern. The β-lactam antibiotics have been used successfully to …

Introduction Pseudomonas aeruginosa nosocomial pneumonia (Pa-NP) is associated with
considerable morbidity, prolonged hospitalization, increased costs, and mortality. Methods …

Class D β-lactamases are composed of 14 families and the majority of the member enzymes
are included in the OXA family. The genes for class D β-lactamases are frequently identified …

The Class D β-lactamases have emerged as a prominent resistance mechanism against β-
lactam antibiotics that previously had efficacy against infections caused by pathogenic …

Antibiotics can truly be considered the symbol of the 20th century's miracle drugs. However,
excessive and inappropriate use of antibiotics in human and veterinary medicine has led to …

OXA-48 is the most common carbapenemase in Enterobacterales in Germany and one of
the most frequent carbapenemases worldwide. Several reports have associated bla OXA …

The worldwide dissemination of extended-spectrum beta-lactamase producing
Enterobacteriaceae,(ESBL-E) and their subset producing carbapenemases (CPE), is …

Objectives To investigate the resistance to carbapenems in Enterobacteriaceae and the
underlying resistance mechanisms in North Lebanon between 2008 and 2012. Methods A …

The OXA-48 carbapenemase is mainly encoded by∼ 62-kb IncL/M plasmids. However,
chromosome-mediated genes have been observed in Escherichia coli isolates. In this work …