Antibody and Nanobody Radiolabeling with Copper-64: Solid vs. Liquid Target Approach

I Hrynchak, D Cocioabă, AI Fonseca, R Leonte… - Molecules, 2023 - mdpi.com
Antibody and nanobody-based copper-64 radiopharmaceuticals are increasingly being
proposed as theranostic tools in multiple human diseases. While the production of copper …

Modifications in cellular viability, DNA damage and stress responses inflicted in cancer cells by copper-64 ions

RM Serban, D Niculae, G Manda, I Neagoe… - Frontiers in …, 2023 - frontiersin.org
Due to combined therapeutical emissions, a high linear energy transfer Auger-electrons with
the longer ranged β− particles, 64Cu-based radiopharmaceuticals raise particular …

[HTML][HTML] Neurotensin (8-13) and Neuromedin N Neuropeptides Radiolabelling with Copper-64 Produced on Solid or Liquid Targets

D Cocioabă, AI Fonseca, R Leonte, I Hrynchak… - Molecules, 2024 - mdpi.com
On the verge of a theranostic approach to personalised medicine, copper-64 is one of the
emerging radioisotopes in nuclear medicine due to its exploitable nuclear and biochemical …

Assessment of chromatography separation parameters in the quality control of copper-64-labeled neurotensin-like peptides

MR Tudoroiu-Cornoiu, EL Chilug, D Cocioabă… - … of Radioanalytical and …, 2024 - Springer
In recent years, research on the Cu-64 effects on malignant tumours has increased, leading
to the development of radiopharmaceuticals with higher selectivity, aiming to target tumour …