Viral infection is controlled by host innate immune cells that express specialized receptors
for viral components. Engagement of these pattern recognition receptors triggers a series of …

A harmonized balance between positive and negative regulation of pattern recognition
receptor (PRR)-initiated immune responses is required to achieve the most favorable …

Abstract N6-methyladenosine (m6A) modification can regulate a variety of biological
processes. However, the implications of m6A modification in lung adenocarcinoma (LUAD) …

Transmission from an infected mosquito to a host is an essential process in the life cycle of
mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva …

In the last years, proteomics has represented a valuable approach to elucidate key aspects
in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved …

Mitochondria are dynamic organelles whose architecture changes depending on the cell's
energy requirements and other signalling events. These structural changes are collectively …

The pentatricopeptide repeat (PPR) family plays a major role in RNA stability, regulation,
processing, splicing, translation, and editing. Leucine-rich PPR-motif-containing protein …

ABSTRACT DNA damage-inducible transcript 3 (DDIT3) plays important roles in
endoplasmic reticulum (ER) stress-induced apoptosis and autophagy, but its role in innate …

COVID-19 is currently a highly pressing health threat and therapeutic strategies to mitigate
the infection impact are urgently needed. Characterization of the SARS-CoV-2 interactome …

Optimal autophagic activity is crucial to maintain muscle integrity, with either reduced or
excessive levels leading to specific myopathies. LGMD2H is a muscle dystrophy caused by …