The microbiome, cancer, and cancer therapy

BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

The gut microbiota in the pathogenesis and therapeutics of inflammatory bowel disease

T Zuo, SC Ng - Frontiers in microbiology, 2018 - frontiersin.org
In the twenty first century, the changing epidemiology of inflammatory bowel disease (IBD)
globally with increasing disease incidence across many countries relates to the altered gut …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …

[HTML][HTML] Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers

M Dsouza, R Menon, E Crossette, SK Bhattarai… - Cell Host & Microbe, 2022 - cell.com
Manipulation of the gut microbiota via fecal microbiota transplantation (FMT) has shown
clinical promise in diseases such as recurrent Clostridioides difficile infection (rCDI) …

[HTML][HTML] Fecal microbiota transplantation: Review and update

JW Wang, CH Kuo, FC Kuo, YK Wang, WH Hsu… - Journal of the Formosan …, 2019 - Elsevier
Fecal microbiota transplantation (FMT) is a method to directly change the recipient's gut
microbiota to normalize the composition and gain a therapeutic benefit. The history of FMT …

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for …

LC McDonald, DN Gerding, S Johnson… - Clinical infectious …, 2018 - academic.oup.com
Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications

JR Allegretti, BH Mullish, C Kelly, M Fischer - The Lancet, 2019 - thelancet.com
Developments in high-throughput microbial genomic sequencing and other systems biology
techniques have given novel insight into the potential contribution of the gut microbiota to …

European consensus conference on faecal microbiota transplantation in clinical practice

G Cammarota, G Ianiro, H Tilg, M Rajilić-Stojanović… - Gut, 2017 - gut.bmj.com
Faecal microbiota transplantation (FMT) is an important therapeutic option for Clostridium
difficile infection. Promising findings suggest that FMT may play a role also in the …

Systematic review with meta‐analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection

MN Quraishi, M Widlak, N Bhala… - Alimentary …, 2017 - Wiley Online Library
Background Clostridium difficile infection (CDI) is the commonest nosocomial cause of
diarrhoea. Faecal microbiota transplantation (FMT) is an approved treatment for recurrent or …

Gut microbiome in modulating immune checkpoint inhibitors

X Li, S Zhang, G Guo, J Han, J Yu - EBioMedicine, 2022 - thelancet.com
Gut microbiome has been increasingly recognized for its influence on a diverse array of
human diseases including cancer, and may also influence the outcome of cancer therapies …