Fasting and cancer: molecular mechanisms and clinical application

A Nencioni, I Caffa, S Cortellino, VD Longo - Nature Reviews Cancer, 2018 - nature.com
The vulnerability of cancer cells to nutrient deprivation and their dependency on specific
metabolites are emerging hallmarks of cancer. Fasting or fasting-mimicking diets (FMDs) …

[HTML][HTML] Autophagy and intermittent fasting: the connection for cancer therapy?

F Antunes, AG Erustes, AJ Costa, AC Nascimento… - Clinics, 2018 - SciELO Brasil
Cancer is a leading cause of death worldwide, and its incidence is continually increasing.
Although anticancer therapy has improved significantly, it still has limited efficacy for tumor …

Fasting-mimicking diet and hormone therapy induce breast cancer regression

I Caffa, V Spagnolo, C Vernieri, F Valdemarin… - Nature, 2020 - nature.com
Approximately 75% of all breast cancers express the oestrogen and/or progesterone
receptors. Endocrine therapy is usually effective in these hormone-receptor-positive …

Dietary interventions and precision nutrition in cancer therapy

C Martínez-Garay, N Djouder - Trends in Molecular Medicine, 2023 - cell.com
In recent years dietary interventions have become a promising tool in cancer treatment and
have demonstrated a powerful ability to alter metabolism and tumor growth, development …

Fasting and caloric restriction in cancer prevention and treatment

S Brandhorst, VD Longo - Metabolism in cancer, 2016 - Springer
Cancer is the second leading cause of death in the USA and among the leading major
diseases in the world. It is anticipated to continue to increase because of the growth of the …

Targeting cancer metabolism: dietary and pharmacologic interventions

C Vernieri, S Casola, M Foiani, F Pietrantonio… - Cancer discovery, 2016 - AACR
Most tumors display oncogene-driven reprogramming of several metabolic pathways, which
are crucial to sustain their growth and proliferation. In recent years, both dietary and …

Fasting and fasting mimicking diets in cancer prevention and therapy

O Blaževitš, M Di Tano, VD Longo - Trends in Cancer, 2023 - cell.com
Fasting mimicking diets (FMDs) are emerging as effective dietary interventions with the
potential to improve healthspan and decrease the incidence of cancer and other age-related …

Diet and chemotherapy: the effects of fasting and ketogenic diet on cancer treatment

F Plotti, C Terranova, D Luvero, M Bartolone… - Chemotherapy, 2020 - karger.com
Introduction: Diet may influence various aspects of human health. In fact, it is well known that
diet can favour or not the development of various human pathologies, like diabetes …

Cyclic fasting-mimicking diet in cancer treatment: Preclinical and clinical evidence

C Vernieri, F Ligorio, D Tripathy, VD Longo - Cell metabolism, 2024 - cell.com
In preclinical tumor models, cyclic fasting and fasting-mimicking diets (FMDs) produce
antitumor effects that become synergistic when combined with a wide range of standard …

Multi‐omics analysis of disulfidptosis regulators and therapeutic potential reveals glycogen synthase 1 as a disulfidptosis triggering target for triple‐negative breast …

J Xie, X Deng, Y Xie, H Zhu, P Liu, W Deng, L Ning… - MedComm, 2024 - Wiley Online Library
Disruption of disulfide homeostasis during biological processes can have fatal
consequences. Excess disulfides induce cell death in a novel manner, termed as …