Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Macrophages and dendritic cells are myeloid cells that play critical roles in immune
responses. Macrophages help to maintain homeostasis through tissue regeneration and the …

The discovery of cytokines and their role in immune and inflammatory disease led to the
development of a plethora of targeted biologic therapies. Later, efforts to understand …

CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily of receptors
expressed on a variety of cell types. The CD40–CD40L interaction gives rise to many …

BMP6 is a central cytokine in the induction of Sjögren's syndrome–associated (SS-
associated) secretory hypofunction. However, the upstream initiation leading to the …

Dendritic cells (DC) have a key role in the initiation and progression of inflammatory arthritis
(IA). In this study, we identified a DC population that derive from monocytes, characterized …

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by
autoimmunity, synovial inflammation and joint destruction. Pannus formation in the synovial …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint pain and
swelling, synovial hyperplasia, cartilage damage, and bone destruction. The mechanisms of …

Vaccination, being able to prevent millions of cases of infectious diseases around the world
every year, is the most effective medical intervention ever introduced. However …

Simple Summary Classic Hodgkin lymphoma (cHL) is one of the most enigmatic study
models of the tumor microenvironment (TME), in which the Hodgkin–Reed Sternberg (HRS) …