Drug-food interactions with a focus on Mediterranean diet

M Spanakis, E Patelarou, A Patelarou - Applied Sciences, 2022 - mdpi.com
There is a growing interest among people in western countries for adoption of healthier
lifestyle habits and diet behaviors with one of the most known ones to be Mediterranean diet …

Drug interactions for patients with respiratory diseases receiving COVID-19 emerged treatments

M Spanakis, A Patelarou, E Patelarou… - International Journal of …, 2021 - mdpi.com
Pandemic of coronavirus disease (COVID-19) is still pressing the healthcare systems
worldwide. Thus far, the lack of available COVID-19-targeted treatments has led scientists to …

Drug-drug interactions among patients hospitalized with COVID-19 in Greece

M Spanakis, P Ioannou, S Tzalis, V Papakosta… - Journal of Clinical …, 2022 - mdpi.com
The modulation of the pharmacological action of drugs due to drug-drug interactions (DDIs)
is a critical issue in healthcare. The aim of this study was to evaluate the prevalence and the …

[HTML][HTML] Evaluation of drug-related problems in chronic kidney disease patients

TM Shouqair, SA Rabbani, SB Sridhar, MT Kurian - Cureus, 2022 - ncbi.nlm.nih.gov
Background Chronic kidney disease (CKD) is a challenging global health problem with
increasing prevalence worldwide. Concurrence of CKD and comorbidities results in the use …

Prevalence and clinical significance of drug–drug and drug–dietary supplement interactions among patients admitted for cardiothoracic surgery in greece

M Spanakis, M Melissourgaki, G Lazopoulos… - Pharmaceutics, 2021 - mdpi.com
Background: Drug interactions represent a major issue in clinical settings, especially for
critically ill patients such as those with cardiovascular disease (CVD) who require …

Deprescribing opportunities for hospitalized patients with end-stage kidney disease on hemodialysis: a secondary analysis of the MedSafer cluster randomized …

J Moryousef, É Bortolussi-Courval… - … Journal of Kidney …, 2022 - journals.sagepub.com
Background: End-stage kidney disease patients on dialysis have a substantial risk of
polypharmacy due their propensity for comorbidity and contact with the health care system …

Potential impact of underlying diseases influencing ADME in nonclinical safety assessment

S Cho, H Jo, YJ Hwang, C Kim, YH Jo… - Food and Chemical …, 2024 - Elsevier
Nonclinical studies involve in vitro, in silico, and in vivo experiments to assess the
toxicokinetics, toxicology, and safety pharmacology of drugs according to regulatory …

Improving Kidney Disease Care: One Giant Leap for Nephrology

M Provenzano, L Hu, E Tringali, M Senatore, R Talarico… - Biomedicines, 2024 - mdpi.com
Nephrology is an ever-evolving field of medicine. The importance of such a discipline is
related to the high clinical impact of kidney disease. In fact, abnormalities of kidney function …

Evaluation of Drug Interactions in Hospitalized Patients with Respiratory Disorders in Greece

M Spanakis, P Ioannou, S Tzalis, F Chouzouri… - … in Respiratory Medicine, 2023 - mdpi.com
Highlights What are the main findings? Patients admitted for hospitalization in Greece due to
respiratory disorders are patients with multimorbidity, polypharmacy, and a high prevalence …

Factors contributing to negative outcomes associated with medications and drug-related problems in kidney replacement therapy—a hospital-based prospective …

A Pereira-Céspedes, A Jiménez-Morales… - Journal of Clinical …, 2024 - mdpi.com
Background: Negative outcomes associated with medications (NOM) and drug-related
problems (DRP) significantly impact individuals with kidney replacement therapy (KRT) …