Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

Zinc is the 24th most abundant element in the Earth's crust. Since the discovery of pure zinc
metal in the 18th century, the main application of zinc metal is as materials. Because zinc …

Over the past decade, large strides have been achieved in the invention of methods for the
direct enantioselective addition of alkynes and metal alkynylide nucleophiles into prochiral …

Propargylamines are an important class of organic compounds that have been widely used
as building blocks for the synthesis of various kinds of chemically and biologically relevant …

A mild method for regioselective formation of 1, 5-substituted 1, 2, 3-triazoles is described.
The zinc-mediated reaction works at room temperature and is successful across a wide …

NiCl2 was found to be a highly efficient and effective catalyst for the one-pot three-
component (A3) coupling of aldehydes, amines, and alkynes to produce propargylamines in …

Propargylamine and its derivatives are important skeletal structure for synthesis of many
nitrogen containing active biological and pharmaceutical compounds. They are classically …

Propargylic amines are highly useful building blocks in organic synthesis, and the
corresponding structural motif has been found in various natural products and compounds of …

An inexpensive and readily available catalyst, Zn (OAc) 2· 2H2O is successfully evaluated
for effective one-pot synthesis of propargylamines with moderate to excellent yields for most …

The multicomponent reaction of aldehydes, amines, and alkynes, known as A3 coupling,
yields propargylamines, a valuable organic scaffold, and has received significant interest …