GSK3: a kinase balancing promotion and resolution of inflammation

L Hoffmeister, M Diekmann, K Brand, R Huber - Cells, 2020 - mdpi.com
GSK3 has been implicated for years in the regulation of inflammation and addressed in a
plethora of scientific reports using a variety of experimental (disease) models and …

Cytokines and signaling networks regulating disease outcomes in leishmaniasis

A Saha, S Roy, A Ukil - Infection and Immunity, 2022 - Am Soc Microbiol
Cytokines play crucial roles in commencing and coordinating the organized recruitment and
activation of immune cells during infection. These molecular regulators play an important …

Osteosarcoma Cell-Derived Exosomal ELFN1-AS1 Mediates Macrophage M2 Polarization via Sponging miR-138-5p and miR-1291 to Promote the Tumorgenesis of …

B Wang, X Wang, P Li, X Niu, X Liang, G Liu… - Frontiers in …, 2022 - frontiersin.org
Background Exosomes play an important role in cell-cell communication by transferring
genetic materials such as long non-coding RNAs (lncRNAs) between cancer cells and tumor …

[HTML][HTML] Glycogen synthase kinase 3β in Toll-like receptor signaling

R Ko, SY Lee - Bmb Reports, 2016 - ncbi.nlm.nih.gov
Toll-like receptors (TLRs) play a critical role in the innate immune response against
pathogens. Each TLR recognizes specific pathogen-associated molecular patterns, after …

Properties of virulence emergence of Leishmania infantum isolates from Phlebotomus perniciosus collected during the human leishmaniosis outbreak in Madrid …

A Mas, A Martínez‐Rodrigo, JA Orden… - Transboundary and …, 2021 - Wiley Online Library
Recent anthropic activity related to the construction of the Bosquesur Green Park in a large
urban setting in Madrid (Spain) has resulted in the largest reported community outbreak of …

Leishmania exploits host cAMP/EPAC/calcineurin signaling to induce an IL-33–mediated anti-inflammatory environment for the establishment of infection

S Roy, S Roy, S Halder, K Jana, A Ukil - Journal of Biological Chemistry, 2024 - ASBMB
Host anti-inflammatory responses are critical for the progression of visceral leishmaniasis,
and the pleiotropic cytokine interleukin (IL)-33 was found to be upregulated in infection …

Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease

G Steinbach, DM Hockenbery, G Huls, T Furlong… - PLoS …, 2017 - journals.plos.org
Severe intestinal graft-vs-host disease (GVHD) after allogeneic hematopoietic cell
transplantation (HCT) causes mucosal ulceration and induces innate and adaptive immune …

LncRNAs act as modulators of macrophages within the tumor microenvironment

K Li, T Xie, Y Li, X Huang - Carcinogenesis, 2024 - academic.oup.com
Long non-coding RNAs (lncRNAs) have been established as pivotal players in various
cellular processes, encompassing the regulation of transcription, translation and post …

Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of Leishmania GSK-3

V Sebastián-Pérez, P Martínez de Iturrate… - Biomedicines, 2022 - mdpi.com
More than 1 billion people live in areas endemic for leishmaniasis, which is a relevant threat
for public health worldwide. Due to the inadequate treatments, there is an urgent need to …

Неанестетические эффекты современных галогенсодержащих анестетиков

ОА Гребенчиков, ЮВ Скрипкин… - Патология …, 2020 - cyberleninka.ru
Огромная когорта пациентов подвергается оперативным вмешательствам в условиях
общей анестезии. Для врачей-анестезиологов одной из приоритетных задач является …