Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits

J Nagai, X Yu, T Papouin, E Cheong, MR Freeman… - Neuron, 2021 - cell.com
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

Norepinephrine links astrocytic activity to regulation of cortical state

ME Reitman, V Tse, X Mi, DD Willoughby… - Nature …, 2023 - nature.com
Cortical state, defined by population-level neuronal activity patterns, determines sensory
perception. While arousal-associated neuromodulators—including norepinephrine (NE) …

[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

BK Hulse, H Haberkern, R Franconville… - Elife, 2021 - elifesciences.org
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

The emerging nature of astrocyte diversity

BS Khakh, B Deneen - Annual review of neuroscience, 2019 - annualreviews.org
Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …

[HTML][HTML] Cell biology of astrocyte-synapse interactions

NJ Allen, C Eroglu - Neuron, 2017 - cell.com
Astrocytes, the most abundant glial cells in the mammalian brain, are critical regulators of
brain development and physiology through dynamic and often bidirectional interactions with …

Making sense of astrocytic calcium signals—from acquisition to interpretation

A Semyanov, C Henneberger, A Agarwal - Nature Reviews …, 2020 - nature.com
Astrocytes functionally interact with neurons and with other brain cells. Although not
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …

Adenosine signalling to astrocytes coordinates brain metabolism and function

SM Theparambil, O Kopach, A Braga, S Nizari… - Nature, 2024 - nature.com
Brain computation performed by billions of nerve cells relies on a sufficient and
uninterrupted nutrient and oxygen supply,. Astrocytes, the ubiquitous glial neighbours of …

Chemico-genetic discovery of astrocytic control of inhibition in vivo

T Takano, JT Wallace, KT Baldwin, AM Purkey, A Uezu… - Nature, 2020 - nature.com
Perisynaptic astrocytic processes are an integral part of central nervous system synapses,;
however, the molecular mechanisms that govern astrocyte–synapse adhesions and how …

Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis

JA Stogsdill, J Ramirez, D Liu, YH Kim, KT Baldwin… - Nature, 2017 - nature.com
Astrocytes are complex glial cells with numerous fine cellular processes that infiltrate the
neuropil and interact with synapses. The mechanisms that control the establishment of …