Advancement in precision diagnosis and therapeutic for triple-negative breast cancer: Harnessing diagnostic potential of CRISPR-cas & engineered CAR T-cells …
Cancer is characterized by uncontrolled cell growth, disrupted regulatory pathways, and the
accumulation of genetic mutations. These mutations across different types of cancer lead to …
accumulation of genetic mutations. These mutations across different types of cancer lead to …
Extracellular vesicles: A new diagnostic biomarker and targeted drug in osteosarcoma
X Gao, B Gao, S Li - Frontiers in Immunology, 2022 - frontiersin.org
Osteosarcoma (OS) is a primary bone cancer that is highly prevalent among adolescents
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …
Functionalized nanomaterials as tailored theranostic agents in brain imaging
R Thangam, R Paulmurugan, H Kang - Nanomaterials, 2021 - mdpi.com
Functionalized nanomaterials of various categories are essential for developing cancer
nano-theranostics for brain diseases; however, some limitations exist in their effectiveness …
nano-theranostics for brain diseases; however, some limitations exist in their effectiveness …
Advances in purification, modification, and application of extracellular vesicles for novel clinical treatments
Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Extracellular vesicles (EV) are membrane vesicles surrounded by a lipid bilayer membrane
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …
The emerging roles of exosomal long non‐coding RNAs in bladder cancer
Q Liu - Journal of cellular and molecular medicine, 2022 - Wiley Online Library
Extracellular vesicles (EVs), especially exosomes, have been reported to play essential
roles as extracellular messengers by transporting goods in various diseases, while their …
roles as extracellular messengers by transporting goods in various diseases, while their …
cGAMP the travelling messenger
HTW Blest, L Chauveau - Frontiers in Immunology, 2023 - frontiersin.org
2'3'-cGAMP is a key molecule in the cGAS-STING pathway. This cyclic dinucleotide is
produced by the cytosolic DNA sensor cGAS in response to the presence of aberrant dsDNA …
produced by the cytosolic DNA sensor cGAS in response to the presence of aberrant dsDNA …
Validating cell surface proteases as drug targets for cancer therapy: what do we know, and where do we go?
E Verhulst, D Garnier, I De Meester, B Bauvois - Cancers, 2022 - mdpi.com
Simple Summary Cell surface proteases (so-called ectoproteases) are associated with
cancer, and their targeting may confer valuable options for the improvement of cancer …
cancer, and their targeting may confer valuable options for the improvement of cancer …
Proteomic analysis reveals microvesicles containing NAMPT as mediators of radioresistance in glioma
Tumor-initiating cells contained within the aggressive brain tumor glioma (glioma stem cells,
GSCs) promote radioresistance and disease recurrence. However, mechanisms of …
GSCs) promote radioresistance and disease recurrence. However, mechanisms of …
Thy-1-Integrin Interactions in cis and Trans Mediate Distinctive Signaling
Thy-1 is a cell surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein that bears a
broad mosaic of biological roles across various cell types. Thy-1 displays strong …
broad mosaic of biological roles across various cell types. Thy-1 displays strong …