Nutrigenetics, epigenetics and gestational diabetes: consequences in mother and child

M Franzago, F Fraticelli, L Stuppia, E Vitacolonna - Epigenetics, 2019 - Taylor & Francis
ABSTRACT Gestational Diabetes Mellitus (GDM) is the most common metabolic condition
during pregnancy and may result in short-and long-term complications for both mother and …

Genetics and epigenetics: new insight on gestational diabetes mellitus

MG Dalfrà, S Burlina, GG Del Vescovo… - Frontiers in …, 2020 - frontiersin.org
Gestational diabetes mellitus (GDM) is the most common metabolic complication of
pregnancy, with a prevalence that has increased significantly in the last decade, coming to …

Immunoendocrine dysregulation during gestational diabetes mellitus: The central role of the placenta

A Olmos-Ortiz, P Flores-Espinosa, L Díaz… - International Journal of …, 2021 - mdpi.com
Gestational Diabetes Mellitus (GDM) is a transitory metabolic condition caused by
dysregulation triggered by intolerance to carbohydrates, dysfunction of beta-pancreatic and …

Genes and diet in the prevention of chronic diseases in future generations

M Franzago, D Santurbano, E Vitacolonna… - International journal of …, 2020 - mdpi.com
Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …

Personalized nutrition in the management of female infertility: new insights on chronic low-grade inflammation

G Fabozzi, G Verdone, M Allori, D Cimadomo… - Nutrients, 2022 - mdpi.com
Increasing evidence on the significance of nutrition in reproduction is emerging from both
animal and human studies, suggesting a mutual association between nutrition and female …

Clinical significance of neutrophil–lymphocyte ratio and monocyte–lymphocyte ratio in women with hyperglycemia

J Wang, QW Zhu, XY Cheng, CX Sha… - Postgraduate …, 2020 - Taylor & Francis
Objective: Abnormal pro-inflammatory regulation of the immune system might contribute to
the pathogenesis of hyperglycemia during pregnancy. We examined the correlations of …

The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes

L del Bosque‐Plata… - Journal of Cellular …, 2022 - Wiley Online Library
The TCF7L2 protein is a key transcriptional effector of the Wnt/β‐catenin signaling pathway,
regulating gene expression. It was initially identified in cancer research and embryologic …

Effects of dietary polyphenols on maternal and fetal outcomes in maternal diabetes

L Zhao, Q Chang, Z Cong, Y Zhang, Z Liu, Y Zhao - Food & Function, 2023 - pubs.rsc.org
The incidences of short-term or long-term adverse maternal and fetal outcomes caused by
maternal diabetes are increasing. Due to toxicity or side effects, economic pressures, and …

The effects of selenium plus probiotics supplementation on glycemic status and serum lipoproteins in patients with gestational diabetes mellitus: A randomized, double …

E Amirani, Z Asemi, M Taghizadeh - Clinical nutrition ESPEN, 2022 - Elsevier
Objective The aim of the current study was to determine the effects of probiotic plus selenium
supplementation on glycemic control and lipid profils in patients with gestational diabetes …

Fat mass and obesity-associated (FTO) gene epigenetic modifications in gestational diabetes: new insights and possible pathophysiological connections

M Franzago, F Fraticelli, M Marchioni, M Di Nicola… - Acta …, 2021 - Springer
Aims Gestational diabetes mellitus (GDM) can lead to short-and long-term complications for
the child. Epigenetic alterations could contribute to explaining the metabolic disturbances …