New trends in platinum and palladium complexes as antineoplastic agents

M Fanelli, M Formica, V Fusi, L Giorgi… - Coordination Chemistry …, 2016 - Elsevier
The discovery of cisplatin (cis-Pt (NH 3) 2 Cl 2) as an antineoplastic agent has focussed
attention on the rational design of metal complexes that can be potentially used in cancer …

Comprehensive review on tumour active palladium compounds and structure–activity relationships

MN Alam, F Huq - Coordination Chemistry Reviews, 2016 - Elsevier
This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

Non-linear optical property and biological assays of therapeutic potentials under in vitro conditions of Pd (II), Ag (I) and Cu (II) complexes of 5-diethyl amino-2-({2-[(2 …

LH Abdel-Rahman, MS Adam, AM Abu-Dief… - Molecules, 2020 - mdpi.com
Herein, we report facile procedures for synthesis of a new Schiff base ligand (H2L, 5-
Diethylamino-2-({2-[(2-hydroxy-benzylidene)-amino]-phenylimino}-methyl)-phenol) and its …

Dithiocarbamates: challenges, control, and approaches to excellent yield, characterization, and their biological applications

AT Odularu, PA Ajibade - Bioinorganic Chemistry and …, 2019 - Wiley Online Library
Progresses made in previous researches on syntheses of dithiocarbamates led to increase
in further researches. This paper reviews concisely the challenges experienced during the …

In Vitro Characterization and Evaluation of the Cytotoxicity Effects of Nisin and Nisin-Loaded PLA-PEG-PLA Nanoparticles on Gastrointestinal (AGS and KYSE-30) …

F Goudarzi, A Asadi, M Afsharpour, RH Jamadi - Aaps Pharmscitech, 2018 - Springer
The aim of this study was an in vitro evaluation and comparison of the cytotoxic effects of
free nisin and nisin-loaded PLA-PEG-PLA nanoparticles on gastrointestinal (AGS and KYSE …

Synthesis and characterization of new guanine complexes of Pt (IV) and Pd (II) by X-Ray diffraction and Hirshfeld surface analysis

AP Novikov, MA Volkov, AV Safonov, MS Grigoriev… - Crystals, 2021 - mdpi.com
The aim of the work was to synthesize new perspective compounds of palladium and
platinum with nitrogenous bases (guanine), promising for use in biomedicine and catalysis …

Bioconjugates of Co (III) complexes with Schiff base ligands and cell penetrating peptides: Solid phase synthesis, characterization and antiproliferative activity

D Śmiłowicz, N Metzler-Nolte - Journal of inorganic biochemistry, 2020 - Elsevier
In this work we synthesized a chelating Schiff base by a single condensation of
salicylaldehyde with 3, 4-diamino benzoic acid (1). This ligand was used further for …

Newly synthesized palladium (II) complexes with aminothiazole derivatives: in vitro study of antimicrobial activity and antitumor activity on the human prostate cancer …

D Simić, M Zarić, I Nikolić, R Živković-Zarić… - Dalton …, 2022 - pubs.rsc.org
Five new complexes of the palladium (II) ion (C1–C5) having the general formula [(PdL2)]
Cl2 with some 2-aminothiazoles (L1–L5), where L1= 2-amino-4-(3, 4-difluorophenyl) …

New palladium (II) and platinum (II) complexes with coumarin based O, N, N pincer: Synthesis, structure elucidation, BSA protein binding studies, and anticancer …

B Bera, S Mondal, S Mandal… - Applied …, 2023 - Wiley Online Library
New Pd (II) and Pt (II) complexes (C1/C2) with a O, N, N donor pincer ligand, 4‐hydroxy‐3‐
((E)‐1‐(((Z)‐phenyl (pyridin‐2‐yl) methylene) hydrazono) ethyl)‐2H‐chromen‐2‐one (HL) …

The palladacycle, BTC2, exhibits anti-breast cancer and breast cancer stem cell activity

S Kimani, S Chakraborty, I Irene, J de la Mare… - Biochemical …, 2021 - Elsevier
In women globally, breast cancer is responsible for most cancer-related deaths and thus,
new effective therapeutic strategies are required to treat this malignancy. Platinum-based …