Real-world big-data studies in laboratory medicine: current status, application, and future considerations

C Ma, X Wang, J Wu, X Cheng, L Xia, F Xue, L Qiu - Clinical Biochemistry, 2020 - Elsevier
With the recent developments in information technology, real world big data studies
(RWBDSs) have attracted increasing attention in the field of medicine. In RWBDSs, clinical …

Free thyroxine measurement in clinical practice: how to optimize indications, analytical procedures, and interpretation criteria while waiting for global standardization

F D'Aurizio, J Kratzsch, D Gruson… - Critical reviews in …, 2023 - Taylor & Francis
Thyroid dysfunctions are among the most common endocrine disorders and accurate
biochemical testing is needed to confirm or rule out a diagnosis. Notably, true …

[HTML][HTML] Reference intervals for thyroid-associated hormones and the prevalence of thyroid diseases in the Chinese population

Y Zou, D Wang, X Cheng, C Ma, S Lin… - Annals of laboratory …, 2021 - synapse.koreamed.org
Background Thyroid diseases are highly prevalent worldwide, but their diagnosis remains a
challenge. We established reference intervals (RIs) for thyroid-associated hormones and …

Reference intervals for thyroid-stimulating hormone, free thyroxine, and free triiodothyronine in elderly Chinese persons

D Wang, S Yu, C Ma, H Li, L Qiu, X Cheng… - Clinical Chemistry and …, 2019 - degruyter.com
Background Thyroid hormone levels are essential for diagnosing and monitoring thyroid
diseases. However, their reference intervals (RIs) in elderly Chinese individuals remain …

Reference interval by the indirect approach of serum thyrotropin (TSH) in a Mediterranean adult population and the association with age and gender

B Lo Sasso, M Vidali, C Scazzone… - Clinical Chemistry and …, 2019 - degruyter.com
Background The serum concentration of thyrotropin (TSH) represents a first-line test in
diagnostic algorithms. The estimation of TSH reference intervals (RIs) is still a matter of …

Validation of an approach using only patient big data from clinical laboratories to establish reference intervals for thyroid hormones based on data mining

C Ma, X Cheng, F Xue, X Li, Y Yin, J Wu, L Xia… - Clinical …, 2020 - Elsevier
Background While many studies have established reference intervals (RIs) for thyroid
hormones using patient data, this approach has not been validated. Therefore, in this study …

Factors influencing the reference interval of thyroid‐stimulating hormone in healthy adults: A systematic review and meta‐analysis

D Xing, D Liu, R Li, Q Zhou, J Xu - Clinical Endocrinology, 2021 - Wiley Online Library
Background Many studies have reported that the thyroid‐stimulating hormone (TSH)
reference interval is susceptible to external factors, such as age, sex, race, region and iodine …

Establishment of reference intervals for serum thyroid‐stimulating hormone, free and total thyroxine, and free and total triiodothyronine for the Beckman Coulter DxI …

Y Wang, Y Zhang, Y Zhou, J Xia - Journal of Clinical Laboratory …, 2017 - Wiley Online Library
Background In order to establish suitable reference intervals of thyroid‐stimulating hormone
(TSH), free (unbound) T4 (FT 4), free triiodothyronine (FT 3), total thyroxine (T4), and total …

Reference intervals for thyrotropin in an area of Northern Italy: the Pordenone thyroid study (TRIPP)

R Tozzoli, F D'Aurizio, P Metus, A Steffan… - Journal of …, 2018 - Springer
Purpose Thyrotropin (TSH) is the most accurate marker of thyroid dysfunction in the absence
of pituitary or hypothalamic disease. Studies on TSH reference intervals (RIs) showed wide …

[HTML][HTML] Reference intervals for thyroid disorders calculated by indirect method and comparison with reference change values

Z Yildiz, LK Dağdelen - Biochemia Medica, 2023 - hrcak.srce.hr
Sažetak IntroductionThe aim of the study was to calculate reference intervals (RIs) for thyroid
stimulating hormone (TSH), free thyroxine (fT4) and free triiodothyronine (fT3) and evaluate …