Beginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to
Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks …

RNA interference (RNAi) technology has been used for almost two decades to study gene
functions and in therapeutic approaches. It uses cellular machinery and small, designed …

Recent Zika virus (ZIKV) outbreaks have highlighted the necessity for development of novel
vector control strategies to combat arboviral transmission, including genetic versions of the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19,
a pandemic associated with substantial morbidity and mortality. Despite of this, no vaccine …

Chikungunya virus (CHIKV) is the causative agent of chikungunya fever (CHIKF) and is
categorized as a (n)(re) emerging arbovirus. CHIKV has repeatedly been responsible for …

Chikungunya virus (CHIKV) is an arthropod-borne alphavirus. Alphaviruses are positive
strand RNA viruses that require a 5′ cap structure to direct translation of the viral …

RNA interference (RNAi) provides the means for alternative antiviral therapy. Delivery of
RNAi in the form of short interfering RNA (siRNA), short hairpin RNA (shRNA) and micro …

Coronaviruses (CoVs) are single-stranded RNA viruses which following virus attachment
and entry into the host cell, particularly type 2 pneumocytes but also endothelial cells …

Chikungunya virus has emerged as one of the most important global arboviral threats over
the last decade. Inspite of large scale morbidity, with long lasting polyarthralgia, so far no …

Human pathogens belonging to the Alphavirus genus, in the Togaviridae family, are
transmitted primarily by mosquitoes. The signs and symptoms associated with these viruses …