Enhancer looping protein LDB1 modulates MYB expression in T-ALL cell lines in vitro by cooperating with master transcription factors

Y Li, Z Zhang, J Yu, H Yin, X Chu, H Cao, Y Tao… - Journal of Experimental …, 2024 - Springer
Background Despite significant progress in the prognosis of pediatric T-cell acute
lymphoblastic leukemia (T-ALL) in recent decades, a notable portion of children still …

BPDCN MYB fusions regulate cell cycle genes, impair differentiation and induce myeloid-dendritic cell leukemia

CAG Booth, JM Bouyssou, K Togami, O Armand… - JCI insight, 2024 - insight.jci.org
MYB fusions are recurrently found in select cancers, including blastic plasmacytoid dendritic
cell neoplasm (BPDCN), an acute leukemia with poor prognosis. They are markedly …