Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics

GS Chaudhry, A Md Akim, YY Sung… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifactorial, multi-stage disease, including complex cascades of signaling
pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the …

The most competent plant-derived natural products for targeting apoptosis in cancer therapy

S Rajabi, M Maresca, AV Yumashev, R Choopani… - Biomolecules, 2021 - mdpi.com
Cancer is a challenging problem for the global health community, and its increasing burden
necessitates seeking novel and alternative therapies. Most cancers share six basic …

Hidden in plants—A review of the anticancer potential of the Solanaceae family in in vitro and in vivo studies

T Kowalczyk, A Merecz-Sadowska, P Rijo, M Mori… - Cancers, 2022 - mdpi.com
Simple Summary The Solanaceae family is one of the most important arable and economic
families in the world. In addition, it includes a wide range of valuable active secondary …

[HTML][HTML] Quercetin induced apoptosis of human oral cancer SAS cells through mitochondria and endoplasmic reticulum mediated signaling pathways

YS Ma, CN Yao, HC Liu, FS Yu, JJ Lin… - Oncology …, 2018 - spandidos-publications.com
Oral cancer is a cause of cancer‑associated mortality worldwide and the treatment of oral
cancer includes radiation, surgery and chemotherapy. Quercetin is a component from …

Sulforaphane induces cell death through G2/M phase arrest and triggers apoptosis in HCT 116 human colon cancer cells

KC Liu, TY Shih, CL Kuo, YS Ma, JL Yang… - The American Journal …, 2016 - World Scientific
Sulforaphane (SFN), an isothiocyanate, exists exclusively in cruciferous vegetables, and has
been shown to possess potent antitumor and chemopreventive activity. However, there is no …

Curcuminoids induce reactive oxygen species and autophagy to enhance apoptosis in human oral cancer cells

YT Hsiao, CL Kuo, FS Chueh, KC Liu… - The American journal …, 2018 - World Scientific
Numerous studies support the use of herbal medicine or natural products for chemotherapy
in human cancers. Reports have associated curcumin (CUR), dimethoxy curcumin (DMC) …

Gemcitabine resistance in non‐small cell lung cancer is mediated through activation of the PI3K/AKT/NF‐κB pathway and suppression of ERK signaling by reactive …

CH Chiu, YJ Lin, S Ramesh, WW Kuo… - … of biochemical and …, 2023 - Wiley Online Library
Lung cancer is one of the most common cancers in the world. Chemotherapy is a standard
clinical treatment. However, tumor cells often develop multidrug resistance after …

Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell migration and invasion via affecting NF‐κB and MMP‐2 and MMP‐9 …

CJ Chen, HS Shang, YL Huang, N Tien… - Environmental …, 2022 - Wiley Online Library
Human glioblastoma (GBM) is one of the common cancer death in adults worldwide, and its
metastasis will lead to difficult treatment. Finding compounds for future to develop treatment …

Research progress on chemical components and pharmacological action of Solanum lyratum Thunb

X Liu, F Wang, Y Chen, Y An, L Cheng… - Journal of Pharmacy …, 2023 - academic.oup.com
Abstract Objectives Solanum lyratum Thunb (SLT) is a perennial plant of the Solanaceae
family, and is extensively used in the clinical practice of traditional Chinese medicine …

Allyl isothiocyanate induces cell toxicity by multiple pathways in human breast cancer cells

P Bo, JC Lien, YY Chen, FS Yu, HF Lu… - The American Journal …, 2016 - World Scientific
Isothiocyanates (ITCs) occur in many cruciferous vegetables. These compounds, which
have significant anticancer actions, can induce apoptosis in different human cancer cell …