Water diffusion in brain tissue is affected by the presence of barriers to translational motion
such as cell membranes and myelin fibers. The measured water apparent diffusion …

In the investigation of ischemic stroke, conventional structural magnetic resonance (MR)
techniques (eg, T1-weighted imaging, T2-weighted imaging, and proton density-weighted …

Water diffusion in a tissue model is studied both analytically and numerically. Tissue is
regarded as a periodic array of boxes surrounded by partially permeable membranes (cells) …

The results of several experimental studies of focal ischemia and anecdotal observations
suggest that leukocytes may contribute to the injury initiated by an arterial occlusion. The …

Diffusion-weighted MRI can rapidly detect acute cerebral ischemic injury as hyperintense
signal changes, reflecting a decline in the apparent diffusion coefficient (ADC) of water …

Objectives: We examined the utility of echoplanar magnetic resonance perfusion imaging
and diffusion-weighted imaging (DWI) in predicting stroke evolution and outcome in 18 …

Cerebral ischemia leads to brain damage caused by pathogenetic mechanisms that are also
activated by neurotrauma. These mechanisms include among others excitotoxicity, over …

Focal brain ischemia induced in rats by occlusion of an intracranial artery is a widely used
paradigm of human brain infarct. Details of the structural changes that develop in either the …

We aimed to determine the frequency and time course of the enlargement of ischemic
cerebral lesions following human stroke and to study the effect of the state of perfusion on …

Background Random motion of water molecules (diffusion) in the presence of a strong
magnetic gradient results in MR signal loss as a result of the dephasing of spin coherence …