Due to the continued emergence of resistance and a lack of new and promising antibiotics,
bacterial infection has become a major public threat. High-throughput screening (HTS) …

The rising burden of antimicrobial resistance and increasing infectious disease outbreaks,
including the recent COVID-19 pandemic, has led to a growing demand for the development …

Natural products (NPs) or their derivatives represent a large proportion of drugs that
successfully progress through clinical trials to approval. This study explores the presence of …

Clostridioides difficile is an enteric pathogen that can cause a range of illnesses from mild
diarrhea to pseudomembranous colitis and even death. This pathogen often takes …

Clostridioides difficile, the causative agent of antibiotic-associated diarrhea and
pseudomembranous colitis, has emerged as a major enteric pathogen in recent years …

Clostridioides difficile infection is a global health threat and remains the primary cause of
hospital-acquired infections worldwide. The burgeoning incidence and severity of infections …

Introduction Clostridioides difficile infection (CDI) remains a worldwide clinical problem.
Increased incidence of primary infection, occurrence of hypertoxigenic ribotypes, and more …

Clostridioides difficile is a major cause of nosocomial infections, often associated with
individuals who have gut dysbiosis from previous antibiotic therapies. C. difficile infections …

Clostridioides difficile is the major cause of antibiotic-associated diarrhea in hospitalized
patients. The low susceptibility of this pathogen to first-line antibiotics coupled with the …

Clostridioides difficile is the leading cause of antibiotic-associated diarrhea referring to
infections of the gastrointestinal tract in the course of (broad-spectrum) antibiotic therapy …