Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

The recent developments of camptothecin and its derivatives as potential anti-tumor agents

X Wang, Y Zhuang, Y Wang, M Jiang, L Yao - European Journal of …, 2023 - Elsevier
This review article focuses on the research progress made in the structural modifications of
camptothecin (CPT), a potent cytotoxic natural alkaloid. CPT possesses a unique 5-fused …

Smart targeting to improve cancer therapeutics

M Morales-Cruz, Y Delgado, B Castillo… - Drug design …, 2019 - Taylor & Francis
Cancer is the second largest cause of death worldwide with the number of new cancer
cases predicted to grow significantly in the next decades. Biotechnology and medicine can …

[HTML][HTML] Research advances in peptide‒drug conjugates

L Gong, H Zhao, Y Liu, H Wu, C Liu, S Chang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Peptide‒drug conjugates (PDCs) are drug delivery systems consisting of a drug covalently
coupled to a multifunctional peptide via a cleavable linker. As an emerging prodrug strategy …

Polysaccharides-based injectable hydrogels: Preparation, characteristics, and biomedical applications

NS El-Sayed, S Kamel - Colloids and Interfaces, 2022 - mdpi.com
Polysaccharides-based injectable hydrogels are a unique group of biodegradable and
biocompatible materials that have shown great potential in the different biomedical fields …

A decade review of triphosgene and its applications in organic reactions

MO Ganiu, B Nepal, JP Van Houten, R Kartika - Tetrahedron, 2020 - Elsevier
This review article highlights selected advances in triphosgene-enabled organic synthetic
reactions that were reported in the decade of 2010–2019. Triphosgene is a versatile reagent …

Cell-penetrating peptides in oncologic pharmacotherapy: A review

N Vale, D Duarte, S Silva, AS Correia, B Costa… - Pharmacological …, 2020 - Elsevier
Cancer is the second leading cause of death in the world and its treatment is extremely
challenging, mainly due to its complexity. Cell-Penetrating Peptides (CPPs) are peptides …

Peptide cargo administration: current state and applications

H Rohira, A Arora, P Kaur, A Chugh - Applied Microbiology and …, 2023 - Springer
Effective delivery of drug molecules to the target site is a challenging task. In the last decade,
several innovations in the drug delivery system (DDS) have tremendously improved the …

Design and application of hybrid cyclic-linear peptide-doxorubicin conjugates as a strategy to overcome doxorubicin resistance and toxicity

S Mozaffari, D Salehi, P Mahdipoor, R Beuttler… - European Journal of …, 2021 - Elsevier
Doxorubicin (Dox) is used for breast cancer, leukemia, and lymphoma treatment as an
effective chemotherapeutic agent. However, Dox use is restricted due to inherent and …