Despite major advances over the past decade, prevention and treatment of type 1 diabetes
mellitus (T1DM) remain suboptimal, with large and unexplained variations in individual …

Canine diabetes is a syndrome resulting from a wide spectrum of clinical pathophysiological
processes that cause a similar set of clinical signs. Various causes of insulin deficiency and …

Background Previous studies of type 1 diabetes in childhood and adolescence have found
large variations in reported incidence around the world. However, it is unclear whether these …

Objective: To describe management strategies that contributed to optimal outcomes in
pediatric recipients of a total pancreatectomy with islet autotransplantation (TPIAT) …

Type 1 diabetes and neurodevelopmental disorders are common chronic conditions in
childhood and adolescence, and having one may lead to an increased chance of …

Background Antibiotics have been associated with several individual autoimmune diseases
(ADs). This study aims to discover whether pre-diagnostic antibiotics are associated with the …

Introduction One of the most important complications of obesity is insulin resistance, which
leads to carbohydrate metabolism disorders such as type 2 diabetes. However, obesity is …

Background Two or more autoantibodies against either insulin (IAA), glutamic acid
decarboxylase (GADA), islet antigen-2 (IA-2A) or zinc transporter 8 (ZnT8A) denote stage 1 …

Childhood-onset obesity has emerged as a major public healthcare challenge across the
globe, fueled by an obesogenic environment and influenced by both genetic and epigenetic …

Type 1 diabetes patients with different residual beta-cell function but similar age, HBA1c,
and cardiorespiratory fitness have differing exercise-induced angiogenic cell mobilisation. 5 …