[HTML][HTML] MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer

G Bertoli, C Cava, I Castiglioni - Theranostics, 2015 - ncbi.nlm.nih.gov
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …

Mechanisms for estrogen receptor expression in human cancer

H Hua, H Zhang, Q Kong, Y Jiang - Experimental hematology & oncology, 2018 - Springer
Estrogen is a steroid hormone that has critical roles in reproductive development, bone
homeostasis, cardiovascular remodeling and brain functions. However, estrogen also …

The many faces of estrogen signaling

P Vrtačnik, B Ostanek, S Mencej-Bedrač, J Marc - Biochemia medica, 2014 - hrcak.srce.hr
Sažetak Estrogens have long been known as important regulators of the female
reproductive functions; however, our understanding of the role estrogens play in the human …

Aberrant regulation and function of microRNAs in cancer

BD Adams, AL Kasinski, FJ Slack - Current Biology, 2014 - cell.com
Malignant neoplasms are consistently among the top four leading causes of death in all age
groups in the United States, despite a concerted effort toward developing novel therapeutic …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Genetic variation in microRNA networks: the implications for cancer research

BM Ryan, AI Robles, CC Harris - Nature reviews cancer, 2010 - nature.com
Many studies have highlighted the role that microRNAs have in physiological processes and
how their deregulation can lead to cancer. More recently, it has been proposed that the …

The different roles of ER subtypes in cancer biology and therapy

C Thomas, JÅ Gustafsson - Nature Reviews Cancer, 2011 - nature.com
By eliciting distinct transcriptional responses, the oestrogen receptors (ERs) ERα and ERβ
exert opposite effects on cellular processes that include proliferation, apoptosis and …

MicroRNAs in cancer

YS Lee, A Dutta - Annual Review of Pathology: Mechanisms of …, 2009 - annualreviews.org
Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the
scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent …

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

DJ Gibbings, C Ciaudo, M Erhardt, O Voinnet - Nature cell biology, 2009 - nature.com
In animals, P-bodies or GW-bodies appear to cause the congregation of proteins involved in
microRNA (miRNA)-mediated post-transcriptional silencing. The localization of P-bodies …

MicroRNA function in cancer: oncogene or a tumor suppressor?

SK Shenouda, SK Alahari - Cancer and metastasis reviews, 2009 - Springer
MicroRNAs (miRNAs) are small noncoding, double-stranded RNA molecules that can
mediate the expression of target genes with complementary sequences. About 5,300 human …