Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …

Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …

Endothelial cells (ECs) constitute small capillary blood vessels and contribute to delivery of
nutrients, oxygen and cellular components to the local tissues, as well as to removal of …

Acute respiratory distress syndrome/chronic obstructive pulmonary disease (ARDS/COPD)
is a diffuse inflammatory injury of the lung that is characterized by respiratory distress and …

Background Hyperoxia-induced lung injury (HILI) is an acute lung injury (LI) induced by
extended periods of exposure to hyperoxia. Alleviating LI by bone marrow mesenchymal …

Lipopolysaccharide (LPS) displays a robust immunostimulatory ability upon Toll-like
receptor 4 (TLR4) recognition. N-methyl-D-aspartate receptors (NMDARs) are highly …

Acute lung injury (ALI) is one of the most common comorbidities associated with sepsis and
can lead to acute respiratory distress syndrome. Intense inflammatory response due to …

Abstract Ethnopharmacological relevance Shufeng Jiedu capsule (SFJDC) is a pure form of
traditional Chinese medicine (TCM) that contains eight medicinal plants. Known for its anti …

Paraquat (PQ), a highly toxic herbicide and primary attack for lung, results in severe acute
lung injury (ALI) appeared as evident oxidative stress, inflammation, and apoptosis …

Three-dimensional hPSC-derived lung organoids resemble the fetal lung stage, making
them an excellent model for studying human lung development. However, current hPSC …