▪ Abstract The polymerization dynamics of microtubules are central to their biological
functions. Polymerization dynamics allow microtubules to adopt spatial arrangements that …

Microtubules have long been considered an ideal target for anticancer drugs because of the
essential role they play in mitosis, forming the dynamic spindle apparatus. As such, there is …

A heat stable protein essentail for microtubule assembly has been isolated. This protein,
which we designate tau (tau), is present in association with tubulin purified from porcine …

Microtubules are cytoskeletal polymers of tubulin involved in many cellular functions. Their
dynamic instability is controlled by numerous compounds and proteins, including colchicine …

Cell Movements vividly describes how complex movements can arise from the properties
and behaviors of biological molecules. This second edition is updated throughout with …

Microtubules can be assembled in vitro from purified α/β tubulin heterodimers in the
presence of GTP. Tubulin is routinely obtained from animal brain tissue through repetitive …

Microtubules, major structural components in cells, are the target of a large and diverse
group of natural product anticancer drugs. Given the success of this class of drugs in cancer …

In this survey, the ionic currents along the microtubules equation handled by applying two
different techniques. It describes the ionic transport throughout the intracellular environment …

Microtubules are dynamic assemblies of αβ‐tubulin heterodimers and have been
recognized as highly attractive targets for cancer chemotherapy. A broad range of agents …

Microtubule assembly is enhanced by the addition of 1 M sucrose or 4 M glycerol to the
reassembly mixture. Tubulin can be purified from guinea pig brain readily and in good yield …