Propagation of the chromatin landscape across cell divisions is central to epigenetic cell
memory. Mechanistic analysis of the interplay between DNA replication, the cell cycle, and …

DNA methylation is essential to development and cellular physiology in mammals. Faulty
DNA methylation is frequently observed in human diseases like cancer and neurological …

Gene expression programmes conferring cellular identity are achieved through the
organization of chromatin structures that either facilitate or impede transcription. Among the …

A multitude of histone chaperones are required to support histones from their biosynthesis
until DNA deposition. They cooperate through the formation of histone co-chaperone …

Faithful inheritance of parental histones is essential to maintain epigenetic information and
cellular identity during cell division. Parental histones are evenly deposited onto the …

Hsp70s comprise a deeply conserved chaperone family that has a central role in
maintaining protein homeostasis. In humans, Hsp70 client specificity is provided by 49 …

Eukaryotic transcription occurs on chromatin, where RNA polymerase II encounters
nucleosomes during elongation. These nucleosomes must unravel for the DNA to enter the …

For shade‐intolerant plants, changes in light quality through competition from neighbors
trigger shade avoidance syndrome (SAS): a series of morphological and physiological …

Tyrosine sulfation is a common posttranslational modification in mammals. To date, it has
been thought to be limited to secreted and transmembrane proteins, but little is known about …

Gene regulation arises out of dynamic competition between nucleosomes, transcription
factors, and other chromatin proteins for the opportunity to bind genomic DNA. The …