Brain-body physiology: Local, reflex, and central communication

M Sammons, MC Popescu, J Chi, SD Liberles… - Cell, 2024 - cell.com
Behavior is tightly synchronized with bodily physiology. Internal needs from the body drive
behavior selection, while optimal behavior performance requires a coordinated …

Neuroimmune recognition and regulation in the respiratory system

J Chen, X Lai, Y Song, X Su - European Respiratory Review, 2024 - publications.ersnet.org
Neuroimmune recognition and regulation in the respiratory system is a complex and highly
coordinated process involving interactions between the nervous and immune systems to …

Lung-innervating nociceptor sensory neurons promote pneumonic sepsis during carbapenem-resistant Klebsiella pneumoniae lung infection

PR Joshi, S Adhikari, C Onah, C Carrier, A Judd… - Science …, 2024 - science.org
Carbapenem-resistant Klebsiella pneumoniae (CRKP) causes Gram-negative lung
infections and fatal pneumonic sepsis for which limited therapeutic options are available …

[HTML][HTML] Sensory neuroimmune interactions at the barrier

Z Wang, K Song, BS Kim, J Manion - Mucosal Immunology, 2024 - Elsevier
Epithelial barriers such as the skin, lung, and gut, in addition to having unique physiologic
functions, are designed to preserve tissue homeostasis upon challenge with a variety of …

Setting the tone: nociceptors as conductors of immune responses

P Hanč, MA Messou, J Ajit, UH von Andrian - Trends in Immunology, 2024 - cell.com
Nociceptors have emerged as master regulators of immune responses in both homeostatic
and pathologic settings; however, their seemingly contradictory effects on the functions of …

[HTML][HTML] Neuro-immune crosstalk in hematopoiesis, inflammation, and repair

DE Akinyemi, R Chevre, O Soehnlein - Trends in Immunology, 2024 - cell.com
Innate immune cells are primary effectors during host defense and in sterile inflammation.
Their production in the bone marrow is tightly regulated by growth and niche factors, and …

The role of nociceptive neurons in allergic rhinitis

J Cong, H Lv, Y Xu - Frontiers in Immunology, 2024 - frontiersin.org
Allergic rhinitis (AR) is a chronic, non-infectious condition affecting the nasal mucosa,
primarily mediated mainly by IgE. Recent studies reveal that AR is intricately associated not …

Sensory sentinels: Neuroimmune detection and food allergy

PR Matatia, E Christian, CL Sokol - Immunological Reviews, 2024 - Wiley Online Library
Food allergy is classically characterized by an inappropriate type‐2 immune response to
allergenic food antigens. However, how allergens are detected and how that detection leads …

The peripheral neuroimmune system

K Song, BS Kim - Journal of Leukocyte Biology, 2024 - academic.oup.com
Historically, the nervous and immune systems were studied as separate entities. The
nervous system relays signals between the body and the brain by processing sensory inputs …

Neuroimmunophysiology of the gastrointestinal tract

DM McKay, M Defaye, S Rajeev… - American Journal …, 2024 - journals.physiology.org
Gut physiology is the epicenter of a web of internal communication systems (ie, neural,
immune, hormonal) mediated by cell-cell contacts, soluble factors, and external influences …