[PDF][PDF] Handbook of life course health development

N Halfon, CB Forrest, RM Lerner, EM Faustman - 2018 - library.oapen.org
Handbook of life course health development Neal Halfon· Christopher B. Forrest Richard M.
Lerner· Elaine M. Faustman Editors Handbook of Life Course Health Development Page 2 …

Dynamical landscapes of cell fate decisions

M Sáez, J Briscoe, DA Rand - Interface focus, 2022 - royalsocietypublishing.org
The generation of cellular diversity during development involves differentiating cells
transitioning between discrete cell states. In the 1940s, the developmental biologist Conrad …

[PDF][PDF] The emerging theoretical framework of life course health development

N Halfon, CB Forrest - Handbook of life course health …, 2018 - library.oapen.org
20 psychology (Lerner 2012), systems biology (Kitano 2002; Antony et al. 2012; Schadt and
Bjorkegren 2012), epigenetics (Egger et al. 2004), the developmental origins of chronic …

Allele-specific epigenome maps reveal sequence-dependent stochastic switching at regulatory loci

V Onuchic, E Lurie, I Carrero, P Pawliczek, RY Patel… - Science, 2018 - science.org
INTRODUCTION A majority of imbalances in DNA methylation between homologous
chromosomes in humans are sequence-dependent; the DNA sequence differences between …

[HTML][HTML] Making sense of the epigenome using data integration approaches

E Cazaly, J Saad, W Wang, C Heckman… - Frontiers in …, 2019 - frontiersin.org
Epigenetic research involves examining the mitotically heritable processes that regulate
gene expression, independent of changes in the DNA sequence. Recent technical …

[HTML][HTML] Attractor dynamics drives self-reproduction in protobiological catalytic networks

A Kahana, L Segev, D Lancet - Cell reports physical science, 2023 - cell.com
The origin of life must have involved an unlikely transition from chaotic chemistry to self-
reproducing supramolecular structures. Previous quantitative analyses of self-reproducing …

Teleonomy in living systems: an overview

RI Vane-Wright, PA Corning - Biological Journal of the Linnean …, 2023 - academic.oup.com
An introduction, overview and discussion are provided for this special issue of the Biological
Journal of the Linnean Society, entitled 'Teleonomy in Living Systems'. The introduction …

Cancer as robust intrinsic state shaped by evolution: a key issues review

R Yuan, X Zhu, G Wang, S Li, P Ao - Reports on Progress in …, 2017 - iopscience.iop.org
Cancer is a complex disease: its pathology cannot be properly understood in terms of
independent players—genes, proteins, molecular pathways, or their simple combinations …

[HTML][HTML] Phenotypic plasticity in prostate cancer: role of intrinsically disordered proteins

SM Mooney, MK Jolly, H Levine… - Asian journal of …, 2016 - journals.lww.com
A striking characteristic of cancer cells is their remarkable phenotypic plasticity, which is the
ability to switch states or phenotypes in response to environmental fluctuations. Phenotypic …

Dissecting Mechanisms of Epigenetic Memory Through Computational Modeling

A Briffa, G Menon… - Annual Review of …, 2024 - annualreviews.org
Understanding the mechanistic basis of epigenetic memory has proven to be a difficult task
due to the underlying complexity of the systems involved in its establishment and …