DNA methylation levels and telomere length in human teeth: usefulness for age estimation

AB Márquez-Ruiz, L González-Herrera… - International Journal of …, 2020 - Springer
In the last decade, increasing knowledge of epigenetics has led to the development of DNA
methylation-based models to predict age, which have shown high predictive accuracy …

Molecular methods for age estimation: The current state of the art in relation to specific demands of forensic practice

P Böhme, A Reckert, J Becker, S Ritz-Timme - Rechtsmedizin, 2021 - Springer
With the increase of globalization and migration, the topic of age estimation has become
more and more important in diverse fields of application, especially for age estimation in …

[HTML][HTML] Molecular clocks in ancient proteins: Do they reflect the age at death even after millennia?

NS Mahlke, S Renhart, D Talaa, A Reckert… - International Journal of …, 2021 - Springer
Age at death estimation in cases of human skeletal finds is an important task in forensic
medicine as well as in anthropology. In forensic medicine, methods based on “molecular …

Age estimation based on different molecular clocks in several tissues and a multivariate approach: an explorative study

J Becker, NS Mahlke, A Reckert, SB Eickhoff… - International journal of …, 2020 - Springer
Several molecular modifications accumulate in the human organism with increasing age.
Some of these “molecular clocks” in DNA and in proteins open up promising approaches for …

[HTML][HTML] Age-Related Changes in Post-Translational Modifications of Proteins from Whole Male and Female Skeletal Elements

E Johnston, M Buckley - Molecules, 2023 - mdpi.com
One of the key questions in forensic cases relates to some form of age inference, whether
this is how old a crime scene is, when in time a particular crime was committed, or how old …

Comparison of collagen features of distinct types of caries-affected dentin

AB Matos, M Reis, Y Alania, CD Wu, W Li… - Journal of Dentistry, 2022 - Elsevier
Objectives To compare the biodegradability, mechanical behavior, and physicochemical
features of the collagen-rich extracellular matrix (ECM) of artificial caries-affected dentin …

Molecular and morphological findings in a sample of oral surgery patients: What can we learn for multivariate concepts for age estimation?

T Siahaan, A Reckert, J Becker… - Journal of forensic …, 2021 - Wiley Online Library
It has already been proposed that a combined use of different molecular and morphological
markers of aging in multivariate models may result in a greater accuracy of age estimation …

[HTML][HTML] Molecular age estimation based on posttranslational protein modifications in bone: why the type of bone matters

L König, J Becker, A Reckert, S Ritz-Timme - International Journal of Legal …, 2023 - Springer
Age-at-death estimation is of great relevance for the identification of unknown deceased
individuals. In skeletonised corpses, teeth and bones are theoretically available for age …

[HTML][HTML] Nutzung von Altersinformationen aus posttranslationalen Proteinmodifikationen und DNA-Methylierung zur postmortalen Lebensaltersschätzung

J Becker, J Naue, A Reckert, P Böhme, S Ritz-Timme - Rechtsmedizin, 2021 - Springer
Zusammenfassung Mit der Identifikation und Beschreibung „molekularer Uhren
“(posttranslationale Proteinmodifikationen, DNA-Methylierung) eröffnen sich neue …

[PDF][PDF] Knochen ist nicht gleich Knochen-auch nicht bei der molekularen Lebensaltersschätzung auf Basis posttranslationaler Proteinmodifikationen

LM König - 2024 - docserv.uni-duesseldorf.de
Zusammenfassung Die Identifikation unbekannter Verstorbener ist für die
Ermittlungsbehörden von zentraler Bedeutung. In einschlägigen Fällen geht es häufig um …