Increasing evidence supports a central role of the immune system in sepsis, but the current
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …

Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …

Sepsis is a major cause of death in intensive care units worldwide. The acute phase of
sepsis is often accompanied by sepsis-associated encephalopathy, which is highly …

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. Myocardial dysfunction, often termed sepsis-induced cardiomyopathy …

Sepsis, a life threating syndrome characterized by organ failure after infection, is the most
common cause of death in hospitalized patients. The treatment of sepsis is generally …

An estimated 14.1 million patients survive sepsis each year. Many survivors experience poor
long-term outcomes, including new or worsened neuropsychological impairment; physical …

Background Bacterial translocation from the gut has been suggested to induce a systemic
inflammatory response syndrome (SIRS) and organ dysfunction. The liver has a pivotal role …

Sepsis pathogenesis is complex and heterogeneous; hence, a precision-medicine strategy
is needed. Acute kidney injury (AKI) following sepsis portends higher mortality …

A State of the Art lecture titled “The role of platelets in sepsis” was presented at the ISTH
congress in 2020. Sepsis is a life‐threatening organ dysfunction caused by a dysregulated …

Introduction: Sepsis is an intractable disorder, which is associated with high risk of organ
dysfunction and even death, while its pathogenesis remains largely unclear. Our study aims …