Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely
on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which …

Altered energy metabolism is a biochemical fingerprint of cancer cells that represents one of
the “hallmarks of cancer”. This metabolic phenotype is characterized by preferential …

Proteins that bind both DNA and RNA typify the ability of a single gene product to perform
multiple functions. Such DNA-and RNA-binding proteins (DRBPs) have unique functional …

Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently
appreciated. In addition to the cytoplasm where the majority of GAPDH is located under the …

Background New studies provide evidence that glyceraldehyde-3-phosphate
dehydrogenase (GAPDH) is not simply a classical glycolytic protein of little interest. Instead …

Glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) has long been recognized as an
important enzyme for energy metabolism and the production of ATP and pyruvate through …

Cancer cells enhance their glycolysis, producing lactate, even in the presence of oxygen.
Glycolysis is a series of ten metabolic reactions catalysed by enzymes whose expression is …

Multidimensional proteins such as glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH)
exhibit distinct activities unrelated to their originally identified functions. Apart from …

Metabolic reprogramming is a hallmark of cancer development, progression, and
metastasis. Several metabolic pathways such as glycolysis, tricarboxylic acid (TCA) cycle …

The role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) being consistently
regarded as the main housekeeping gene and reference gene/protein for expression …