[HTML][HTML] A review and comparative study of cancer detection using machine learning: SBERT and SimCSE application

M Mokoatle, V Marivate, D Mapiye, R Bornman… - BMC …, 2023 - Springer
Background Using visual, biological, and electronic health records data as the sole input
source, pretrained convolutional neural networks and conventional machine learning …

[HTML][HTML] Swarm learning for decentralized artificial intelligence in cancer histopathology

OL Saldanha, P Quirke, NP West, JA James… - Nature medicine, 2022 - nature.com
Artificial intelligence (AI) can predict the presence of molecular alterations directly from
routine histopathology slides. However, training robust AI systems requires large datasets …

[HTML][HTML] Adversarial attacks and adversarial robustness in computational pathology

N Ghaffari Laleh, D Truhn, GP Veldhuizen… - Nature …, 2022 - nature.com
Artificial Intelligence (AI) can support diagnostic workflows in oncology by aiding diagnosis
and providing biomarkers directly from routine pathology slides. However, AI applications …

[HTML][HTML] Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective …

HS Muti, LR Heij, G Keller, M Kohlruss… - The Lancet Digital …, 2021 - thelancet.com
Background Response to immunotherapy in gastric cancer is associated with microsatellite
instability (or mismatch repair deficiency) and Epstein-Barr virus (EBV) positivity. We …

[HTML][HTML] Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study

JM Niehues, P Quirke, NP West, HI Grabsch… - Cell reports …, 2023 - cell.com
Deep learning (DL) can predict microsatellite instability (MSI) from routine histopathology
slides of colorectal cancer (CRC). However, it is unclear whether DL can also predict other …

[HTML][HTML] Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma

J Calderaro, N Ghaffari Laleh, Q Zeng, P Maille… - Nature …, 2023 - nature.com
Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to
hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined …

[HTML][HTML] Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application

A Echle, NG Laleh, P Quirke, HI Grabsch, HS Muti… - ESMO open, 2022 - Elsevier
Background Microsatellite instability (MSI)/mismatch repair deficiency (dMMR) is a key
genetic feature which should be tested in every patient with colorectal cancer (CRC) …

Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer

S Brockmoeller, A Echle, N Ghaffari Laleh… - The Journal of …, 2022 - Wiley Online Library
The spread of early‐stage (T1 and T2) adenocarcinomas to locoregional lymph nodes is a
key event in disease progression of colorectal cancer (CRC). The cellular mechanisms …

[HTML][HTML] Artificial intelligence–based detection of FGFR3 mutational status directly from routine histology in bladder cancer: a possible preselection for molecular …

CML Loeffler, NO Bruechle, M Jung, L Seillier… - European urology …, 2022 - Elsevier
Background Fibroblast growth factor receptor (FGFR) inhibitor treatment has become the first
clinically approved targeted therapy in bladder cancer. However, it requires previous …

[HTML][HTML] End-to-end prognostication in colorectal cancer by deep learning: a retrospective, multicentre study

X Jiang, M Hoffmeister, H Brenner, HS Muti… - The Lancet Digital …, 2024 - thelancet.com
Background Precise prognosis prediction in patients with colorectal cancer (ie, forecasting
survival) is pivotal for individualised treatment and care. Histopathological tissue slides of …