Lung cancer is the most devastating malignancy in the world. Beyond genetic research,
epigenomic studies—especially investigations of microRNAs—have grown rapidly in …

Recently, targeting metabolic reprogramming has emerged as a potential therapeutic
approach for fighting cancer. Sterol regulatory element binding protein-2 (SREBP-2), a basic …

Abstract Background MicroRNAs (miRNAs) and Twist1-induced epithelial-mesenchymal
transition (EMT) in cancer cell dissemination are well established, but the involvement of …

Abstract Methyltransferase like 3 (METTL3) was incipiently known as a methyltransferase
which was responsible for N 6-methyladenosine (m 6 A) methylation. METTL3 can promote …

TWIST1 is a basic helix-loop-helix (bHLH) transcription factor which plays essential and
pivotal roles in multiple stages of embryonic development, and significantly contributes to …

Lung cancer remains the number one cause of cancer-related deaths worldwide with
221,200 estimated new cases and 158,040 estimated deaths in 2015. Approximately 80% of …

Colorectal cancer (CRC) is responsible for one of the major cancer incidence and mortality
worldwide. It is well known that MicroRNAs (miRNAs) play vital roles in maintaining the cell …

Epithelial–mesenchymal transition (EMT) has been recognized as a key element of cell
migration and invasion in lung cancer; however, the underlying mechanisms are not fully …

MicroRNAs (MiRNAs) have been found to be dysregulated in lung cancer tissues compared
to their matched paracancerous tissues. However, the roles of miRNAs in peripheral blood …

Epithelial to mesenchymal transition (EMT) is a central regulatory program that is similar in
many aspects to several steps of embryonic morphogenesis. In addition to its physiological …