Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mainly involving
synovial inflammation and articular bone destruction. RA is a heterogeneous disease with …

Rheumatoid arthritis (RA) is an autoimmune/inflammatory disease affecting 0.5 to 1% of
adults worldwide and frequently leads to joint destruction and disability. Early diagnosis and …

The presence of autoantibodies is one of the hallmarks of rheumatoid arthritis (RA). In the
past few decades, rheumatoid factors (autoantibodies that recognize the Fc-tail of …

Introduction In rheumatoid arthritis (RA), several genetic risk factors and smoking are
strongly associated with the presence of anticitrullinated protein antibodies (ACPA), while …

Carbamylation is a non-enzymatic post-translational modification in which cyanate binds to
molecules containing primary amine or thiol groups and forms carbamyl groups. Cyanate is …

Objective. Anti-carbamylated protein (anti-CarP) antibodies could further elucidate early
rheumatoid arthritis (RA) pathogenesis and predict clinical disease. We compared the …

Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease characterized by
extensive synovitis resulting in erosions of articular cartilage and marginal bone with joint …

Objective In rheumatoid arthritis (RA), anti–citrullinated protein antibodies (ACPA s) and
rheumatoid factor (RF) are commonly used to aid in the diagnosis. Although these …

Autoantibody production occurs in juvenile idiopathic arthritis (JIA) and numerous other
autoimmune diseases. In some conditions, the autoantibodies are clearly pathogenic …

Carbamylation describes a nonenzymatic posttranslational protein modification mediated by
cyanate, a dissociation product of urea. When kidney function declines and urea …