During pregnancy, the fetus represents a natural allograft that is not normally rejected. While
the maternal immune system retains the ability to respond to foreign antigens, tolerance …

Despite excellent short-term results, long-term survival of transplanted kidneys has not
improved accordingly. Although alloimmune responses and calcineurin inhibitor-related …

Multiple sclerosis (MS) is more common in females than males and frequently affects women
during their reproductive years. Thus, issues surrounding pregnancy and reproduction are of …

The most abundant lymphocyte present in decidual tissue is the CD8+ T cell. It has been
shown that most decidual CD8+ T cells have an effector-memory phenotype, but expressed …

During pregnancy, the maternal immune system must tolerate the developing foetus, and yet
retain a potent antimicrobial response to prevent infections. Mucosal associated invariant T …

REPRODUCTION Page 1 REPRODUCTION © 2016 Society for Reproduction and Fertility
DOI: 10.1530/REP-15-0608 ISSN 1470–1626 (paper) 1741–7899 (online) Online version …

In oocyte donation (OD) pregnancies, there is a higher level of antigenic dissimilarity
between mother and fetus compared with naturally conceived (NC) pregnancies. We …

Problem Chronic histiocytic intervillositis (CHIV) is a rare type of placental pathology that is
associated with reproductive loss at all gestational ages. The aim of the study was to …

Little is known about the recovery of the immune system from normal pregnancy and
whether the postpartum period is a uniquely adapted immune state. This report extends …

Induction of maternal-fetal immune tolerance is essential for the development of normal
pregnancy. Impaired expression of costimulatory molecules may lead to intense …