Abstract The Zonule of Zinn, or ciliary zonule, is the elaborate system of extracellular fibers
that centers the lens in the eye. In humans, the fibers transmit forces that flatten the lens …

Fibrillin is an evolutionarily ancient protein that lends elasticity and resiliency to a variety of
tissues. In humans, mutations in fibrillin-1 cause Marfan and related syndromes, conditions …

Marfan syndrome is an inherited connective tissue disorder that affects the cardiovascular,
musculoskeletal, and ocular systems. It is caused by pathogenic variants in the fibrillin-1 …

Latent-transforming growth factor beta-binding protein 2 (LTBP-2) is a major component of
arterial and lung tissue and of the ciliary zonule, the system of extracellular fibers that …

Purpose To explore the synergistic function of the ligaments in eye, the zonular fibres, that
mediate change in eye lens shape to allow for focussing over different distances. Methods A …

Introduction: Crystalline lens overshooting refers to a situation in which the lens momentarily
shifts too much from its typical location immediately after stopping the rotational movement of …

Mechanical failure of the ciliary zonule characterizes several ocular and systemic diseases.
The mouse has emerged as a useful model system to investigate the composition and …

Airbags are safety devices in vehicles effectively suppressing passengers' injuries during
accidents. Although there are still many cases of eye injuries reported due to eye-airbag …

Elasticity is essential to the function of tissues such as blood vessels, muscles, and lungs.
This property is derived mostly from the extracellular matrix (ECM), the protein meshwork …

Purpose: To evaluate and compare the mechanical resistance to tearing of the anterior lens
capsule opening after staining with different concentrations of trypan blue in ex vivo porcine …