How leisure activities affect health: a narrative review and multi-level theoretical framework of mechanisms of action

D Fancourt, H Aughterson, S Finn, E Walker… - The Lancet …, 2021 - thelancet.com
There is a large and growing body of evidence on the health benefits of engagement in
leisure activities (voluntary, enjoyable non-work activities, such as hobbies, arts …

How can dementia and disability be prevented in older adults: where are we today and where are we going?

I Lisko, J Kulmala, M Annetorp… - Journal of internal …, 2021 - Wiley Online Library
Ageing of the population, together with population growth, has brought along an ample
increase in the number of older individuals living with dementia and disabilities. Dementia is …

Twelve-year clinical trajectories of multimorbidity in a population of older adults

DL Vetrano, A Roso-Llorach, S Fernández… - Nature …, 2020 - nature.com
Multimorbidity—the co-occurrence of multiple diseases—is associated to poor prognosis,
but the scarce knowledge of its development over time hampers the effectiveness of clinical …

[HTML][HTML] Prevention of dementia in an ageing world: Evidence and biological rationale

G Grande, C Qiu, L Fratiglioni - Ageing research reviews, 2020 - Elsevier
As the population ages, the number of people with dementia is expected to increase in the
coming decades, with consequences at the societal and individual levels. In this narrative …

Multimorbidity of chronic non-communicable diseases in low-and middle-income countries: a scoping review

F Abebe, M Schneider, B Asrat… - Journal of …, 2020 - journals.sagepub.com
Background: Multimorbidity is rising in low-and middle-income countries (LMICs). However,
the evidence on its epidemiology from LMICs settings is limited and the available literature …

Multimorbidity burden and dementia risk in older adults: the role of inflammation and genetics

G Grande, A Marengoni, DL Vetrano… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction We investigate dementia risk in older adults with different disease patterns and
explore the role of inflammation and apolipoprotein E (APOE) genotype. Methods A total of …

The effects of lifestyle and diet on gut microbiota composition, inflammation and muscle performance in our aging society

B Strasser, M Wolters, C Weyh, K Krüger, A Ticinesi - Nutrients, 2021 - mdpi.com
Living longer is associated with an increased risk of chronic diseases, including impairments
of the musculoskeletal and immune system as well as metabolic disorders and certain …

[HTML][HTML] Measuring gait speed to better identify prodromal dementia

G Grande, F Triolo, A Nuara, AK Welmer… - Experimental …, 2019 - Elsevier
Slow gait speed has been shown to predict incident dementia and cognitive decline in older
individuals. We aimed to summarize the evidence concerning the association of slow gait …

Sarcopenia, long‐term conditions, and multimorbidity: findings from UK Biobank participants

RM Dodds, A Granic, SM Robinson… - Journal of cachexia …, 2020 - Wiley Online Library
Background Sarcopenia, the loss of muscle strength and mass, predicts adverse outcomes
and becomes common with age. There is recognition that sarcopenia may occur at younger …

Number of chronic conditions and associated functional limitations among older adults: cross-sectional findings from the longitudinal aging study in India

P Sharma, P Maurya, T Muhammad - BMC geriatrics, 2021 - Springer
Background Chronic conditions reduce the likelihood of physical functioning among older
adults. However, the contribution of most prevalent diseases and multimorbidity to different …