Peptide-based agents for cancer treatment: current applications and future directions

NTT Nhàn, T Yamada, KH Yamada - International Journal of Molecular …, 2023 - mdpi.com
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …

Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review

Z Chen, M Xiong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …

Three rounds of stability-guided optimization and systematical evaluation of oncolytic peptide LTX-315

XY Fu, H Yin, XT Chen, JF Yao, YN Ma… - Journal of Medicinal …, 2024 - ACS Publications
Oncolytic peptides represent promising novel candidates for anticancer treatments. In our
efforts to develop oncolytic peptides possessing both high protease stability and durable …

Total wash elimination for solid phase peptide synthesis

JM Collins, SK Singh, TA White, DJ Cesta… - Nature …, 2023 - nature.com
We present a process for solid phase peptide synthesis (SPPS) that completely eliminates
all solvent intensive washing steps during each amino acid addition cycle. A key …

[HTML][HTML] Assessment of plant-and microbial-derived protein hydrolysates as sustainable for fetal bovine serum in seafood cell culture media

A Amirvaresi, R Ovissipour - Future Foods, 2024 - Elsevier
This study seeks to explore alternatives by substituting or reducing the conventional 10%
serum concentration in zebrafish embryonic stem cell (ESC) growth media with protein …

Gut-liver axis calibrates intestinal stem cell fitness

G Kim, Z Chen, J Li, J Luo, F Castro-Martinez… - Cell, 2024 - cell.com
The gut and liver are recognized to mutually communicate through the biliary tract, portal
vein, and systemic circulation. However, it remains unclear how this gut-liver axis regulates …

The Use of Immune Regulation in Treating Head and Neck Squamous Cell Carcinoma (HNSCC)

CW Wang, PK Biswas, A Islam, MK Chen, PJ Chueh - Cells, 2024 - mdpi.com
Immunotherapy has emerged as a promising new treatment modality for head and neck
cancer, offering the potential for targeted and effective cancer management. Squamous cell …

[HTML][HTML] Short Peptides as Powerful Arsenal for Smart Fighting Cancer

J Bojarska, WM Wolf - Cancers, 2024 - mdpi.com
Simple Summary This mini-review summarizes the up-to-date progress in developing
anticancer therapies based on cutting-edge strategies employing short peptides. This work …

The Emerging Era of Molecular Medicine

H Tang, Y Zhang, Y Wu, T Fu, C Cui, Z Wang, S Xie… - ACS …, 2024 - ACS Publications
The era of molecular medicine arose as we began to diagnose and treat diseases based on
understanding how genes, proteins, and cells work, providing optimal therapeutic care …

Lighthouses Illuminating Tumor Metastasis: The Application of Fluorescent Probes in the Localization and Imaging Metastatic Lymph Nodes Across Various Tumors

Q Dang, L Zhang, H Ma, X Sun, A Ren, J Chen… - Biomaterials, 2024 - Elsevier
The significance of metastatic lymph nodes in tumor diagnosis and prognosis is self-evident.
With the deepening of research on the lymphatic system and the advancement of imaging …