Glioblastoma (GBM) is the most deadly type of malignant brain tumor, despite extensive
molecular analyses of GBM cells. In recent years, the tumor microenvironment (TME) has …

Primary lung cancer is one of the most common malignant tumors in China. Approximately
60% of lung cancer patients have distant metastasis at the initial diagnosis, so it is …

Diffuse midline glioma-H3K27M mutant (DMG) and glioblastoma (GBM) are the most lethal
brain tumors that primarily occur in pediatric and adult patients, respectively. Both tumors …

Glioblastoma, a subset of aggressive brain tumors, deploy several means to increase blood
vessel supply dedicated to the tumor mass. This includes typical program borrowed from …

Tissue clearing for whole organ cell profiling has revolutionized biology and imaging for
exploration of organs in three-dimensional space without compromising tissue architecture …

Patient‐derived tumor xenograft (PDX) models, a method involving the surgical extraction of
tumor tissues from cancer patients and subsequent transplantation into immunodeficient …

Glioblastomas are highly heterogeneous brain tumors. Despite the availability of standard
treatment for glioblastoma multiforme (GBM), ie, Stupp protocol, which involves surgical …

The cancer burden continues to grow globally, and drug resistance remains a substantial
challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia …

Glioblastoma multiforme, the deadliest primary brain tumor, is characterized by an excessive
and aberrant neovascularization. The initial expectations raised by anti-angiogenic drugs …

Tumor heterogeneity, a hallmark of cancer, impairs the efficacy of cancer therapy and drives
tumor progression. Exploring inter-and intra-tumoral heterogeneity not only provides insights …